Calcipotriol Impurity 22 CAS 125732-36-7
| CAS No. | 125732-36-7 |
| Molecular Formula | C28H44O2 |
| Molecular Weight | 412.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Calcipotriol Impurity 22 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Calcipotriol Impurity 22 (CAS 125732-36-7) is a certified pharmaceutical impurity reference standard with the molecular formula C28H44O2 and a molecular weight of 412.65 g/mol.
The molecular framework of Calcipotriol Impurity 22 (C28H44O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H44O2 |
| Molecular Weight | 412.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
Related Calcipotriol Standards
- Calcipotriol Impurity 20 (CAS 127516-23-8)
- Calcipotriol Impurity 37 (CAS CATO-C4X-122237)
- Calcipotriol (CAS 112828-00-9)
- Calcipotriol Impurity A (CAS 126860-84-2)
- Calcipotriol Impurity 13 (CAS 112849-47-5)
- Calcipotriol EP Impurity B (CAS 2948288-30-8)
- Calcipotriol Impurity 25 (CAS CATO-C4X-122225)
- Calcipotriol EP Impurity C (CAS 113082-99-8)
Recommended Standards
- trans-Doxercalciferol (CAS 74007-20-8)
- Thioctic Acid Impurity 44 (CAS 6718-96-3)
- 21-(tert-Butoxy)-21-oxohenicosanoic acid (CAS 3046115-41-4)
- Thioctic Acid Impurity 24 (CAS CATO-C4X-152653)
- Ubenimex Impurity 2 (CAS 1654771-89-7)
- Brivaracetam Impurity 115 (CAS CATO-C4X-2007115)
- Perindopril Impurity 38 (CAS 80828-13-3)
- N'-((1H-Indol-3-yl)methylene)-4-((4-methylbenzyl)oxy)benzohydrazide (CAS 765311-60-2)
- 4-(2,2,2-Trifluoroethyl)phenol (CAS 86571-21-3)
- 1024308-68-6 (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)-N-(4-(3-(trifluoromethyl)phenoxy)phenyl)formamide MFCD00245948 (CAS 1024308-68-6)
- N'-Cyanobenzenecarboximidamide (CAS 17513-09-6)
- Ethyl (1S,2R,3R,5R)-2-((tert-butoxycarbonyl)amino)-6-oxabicyclo[3.1.0]hexane-3-carboxylate (CAS 959745-87-0)
- 3-((1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl)amino)propan-1-ol (CAS 1249240-84-3)
- Neuropeptide AF (human) (CAS 192387-38-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com