3-Chlorosulfonyl-5-trifluoromethyl-4-(2-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester CAS 1431555-27-9
| CAS No. | 1431555-27-9 |
| Molecular Formula | C14H7ClF6O4S2 |
| Molecular Weight | 452.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chlorosulfonyl-5-trifluoromethyl-4-(2-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester (C14H7ClF6O4S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-Chlorosulfonyl-5-trifluoromethyl-4-(2-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester (CAS 1431555-27-9), a certified reference material (molecular formula C14H7ClF6O4S2, MW 452.78 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chlorosulfonyl-5-trifluoromethyl-4-(2-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF6O4S2 |
| Molecular Weight | 452.78 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 2 |
Related Chlorosulfonyl Standards
- 3-(Chlorosulfonyl)-4-(hexadecyloxy)benzoic acid (CAS 2488-47-3)
- 5-(Chlorosulfonyl)-2-(hexadecyloxy)benzoic acid (CAS 5355-07-7)
- 3-((4-(Chlorosulfonyl)-2-nitrophenyl)sulfonyl)benzenesulfonic acid (CAS 90352-55-9)
- 5,7-Bis(chlorosulfonyl)-9-oxo-9H-xanthene-2-carboxylic acid (CAS 50541-58-7)
- 3-Chlorosulfonyl-4-(2-methoxy-phenyl)-5-trifluoro-methyl-thiophene-2-carboxylic acid methyl ester (CAS 1431555-14-4)
- 4-(3-(5-(Chlorosulfonyl)naphthalen-1-yl)ureido)benzoic acid (CAS 1032507-49-5)
- Ethyl 4-(chlorosulfonyl)-2-methyl-1,5-diphenyl-1H-pyrrole-3-carboxylate (CAS 306936-29-8)
- 3-Chlorosulfonyl-4-(2-hydroxy-phenyl)-5-trifluoro-methyl-thiophene-2-carboxylic acid methyl ester (CAS 1431555-15-5)
Recommended Standards
- DL-erythro-4-Fluoroglutamic acid (CAS 91383-48-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl 3-(trifluoromethyl)benzoate (CAS 321430-26-6)
- 2,3,4,6-Tetrabromo-5-methoxy-N-methylaniline (CAS 1823870-81-0)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide (CAS 856189-81-6)
- Benzyl-2-Chloro-1,1,2-Trifluoroethyl Sulfide (CAS 82789-49-9)
- 4-Amino-3,5-dichloro-N-cyclopropylbenzamide (CAS 60676-83-7)
- (4AR,5S)-8-nitro-1H,2H,3H,4H,4aH,5H,6H-pyrido[1,2-a]quinoline-5-carboxylic acid (CAS 1486485-13-5)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-nitropyridin-2-amine (CAS 61963-63-1)
- 2-(3-((Tert-butoxycarbonyl)amino)piperidin-1-yl)acetic acid (CAS 1353972-52-7)
- (Z)-3-(2,4-Dichlorophenyl)acrylic acid (CAS 20595-46-4)
- N-(2,5-dimethoxybenzyl)-1-(4-methoxyphenyl)methanamine hydrobromide (CAS 1609407-14-8)
- 4-Bromo-3-(difluoromethyl)-5-iodopicolinoyl chloride (CAS 1804952-11-1)
- 2-(Methyl(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethanol (CAS 6266-71-3)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com