4-Chlorosulfonyl-2-trifluoromethyl-[2,3]-bithiophenyl-5-carboxylic acid methyl ester CAS 1431555-28-0
| CAS No. | 1431555-28-0 |
| Molecular Formula | C11H6ClF3O4S3 |
| Molecular Weight | 390.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chlorosulfonyl-2-trifluoromethyl-[2,3]-bithiophenyl-5-carboxylic acid methyl ester.
CATO supplies 4-Chlorosulfonyl-2-trifluoromethyl-[2,3]-bithiophenyl-5-carboxylic acid methyl ester (CAS 1431555-28-0), a certified reference material (molecular formula C11H6ClF3O4S3, MW 390.81 g/mol) for analytical method development and quality control.
4-Chlorosulfonyl-2-trifluoromethyl-[2,3]-bithiophenyl-5-carboxylic acid methyl ester (C11H6ClF3O4S3) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chlorosulfonyl-2-trifluoromethyl-[2,3]-bithiophenyl-5-carboxylic acid methyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF3O4S3 |
| Molecular Weight | 390.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 3 |
Related Chlorosulfonyl Standards
- Benzyl 4-(4-(chlorosulfonyl)phenyl)piperazine-1-carboxylate (CAS 125393-31-9)
- Benzyl 5-(chlorosulfonyl)-7-nitro-2,3-dihydro-1H-indole-1-carboxylate (CAS 1710628-73-1)
- 5-[[p-(Chlorosulfonyl)phenyl]azo]salicylic Acid Methyl Ester Acetate (CAS 34265-47-9)
- Methyl 3-(chlorosulfonyl)-4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 306935-98-8)
- 3-Chlorosulfonyl-4-(2-hydroxy-phenyl)-5-trifluoro-methyl-thiophene-2-carboxylic acid methyl ester (CAS 1431555-15-5)
- Ethyl 4-(chlorosulfonyl)-2-methyl-1,5-diphenyl-1H-pyrrole-3-carboxylate (CAS 306936-29-8)
- 4-(3-(5-(Chlorosulfonyl)naphthalen-1-yl)ureido)benzoic acid (CAS 1032507-49-5)
- 2,4-bis(chlorosulfonyl)phenyl pivalate (CAS CATO-C4X-212340)
Recommended Standards
- Afatinib Impurity 61 (CAS CATO-C4X-100661)
- [(Z)-2-(Benzenesulfonyl)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]dimethylamine (CAS 338758-54-6)
- Afatinib Impurity 60 (CAS CATO-C4X-100660)
- 2-((2-Chlorophenyl)thio)-5-(3-(trifluoromethyl)phenyl)nicotinonitrile (CAS 338964-71-9)
- Pioglitazone Bromo Impurity (CAS 669716-58-9)
- Methyl 3-amino-5-methyl-1H-pyrazole-4-carboxylate (CAS 109012-96-6)
- 1,3,4-Trichloronaphthalen-2-ol (CAS 56961-40-1)
- 2-Amino-N-cyclopropyl-3-methyl-N-(((S)-1-methylpiperidin-2-yl)methyl)butanamide (CAS 1354028-54-8)
- 5-Aminopentanimidamide (CAS 1502317-24-9)
- Tert-butyl 4-(2-oxoimidazolidin-1-yl)piperidine-1-carboxylate (CAS 902133-63-5)
- Trametinib impurity 04 (CAS 871700-25-3)
- 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluoro-10-thiocyanatodecane (CAS 26650-10-2)
- 2-(Isopropyl(1-methylpiperidin-3-yl)amino)acetic acid (CAS 1353951-42-4)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com