2-(bromomethyl)-5-chloro-1,3-benzothiazole CAS 143163-72-8
| CAS No. | 143163-72-8 |
| Molecular Formula | C8H5BrClNS |
| Molecular Weight | 262.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(bromomethyl)-5-chloro-1,3-benzothiazole (CAS 143163-72-8) is a high-purity analytical reference standard with the molecular formula C8H5BrClNS and a molecular weight of 262.55 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine/bromine substitution, 2-(bromomethyl)-5-chloro-1,3-benzothiazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClNS |
| Molecular Weight | 262.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related bromomethyl Standards
- 2-(Bromomethyl)-4-chlorothieno[3,2-c]pyridine (CAS 209286-63-5)
- 2-(Bromomethyl)-7-chlorobenzo[d]thiazole (CAS 848696-95-7)
- 3-(Bromomethyl)-7-chlorothieno[2,3-c]pyridine (CAS 209286-60-2)
- 1-[4-(bromomethyl)piperidin-1-yl]-3-methylbutan-1-one (CAS 1061458-59-0)
- 1-[3-(bromomethyl)piperidin-1-yl]-2,2-dimethylpropan-1-one (CAS 1082786-50-2)
- 4-(Bromomethyl)nicotinonitrile (CAS 116986-15-3)
- 2-(4-(Bromomethyl)phenyl)-5-methylpyridine (CAS 1119454-23-7)
- 3-Bromomethyl-2-methyl-6-phenylpyridine, 97% (CAS 1397229-75-2)
Recommended Standards
- 4-Bromo-5-chloro-2-methylbenzo[d]thiazole (CAS 1427384-48-2)
- 3-Bromo-2-chlorobenzo[b]thiophen-5-amine (CAS 1935534-79-4)
- 6-Bromo-4-chloro-2-methylbenzo[d]thiazole (CAS 1427363-00-5)
- 7-Bromo-2-chloro-4-methylbenzo[d]thiazole (CAS 1190321-90-4)
- 9-Chloro-10-(dimethoxymethyl)anthracene (CAS 848478-89-7)
- 5-Chloro-3-methoxy-2-methylaniline (CAS 1195519-80-2)
- Ethyl (E)-(3-((2-carbamothioylhydrazono)methyl)thiophen-2-yl)carbamate (CAS 1048915-72-5)
- 2-(3-Chloro-2-(trifluoromethyl)pyridin-4-yl)ethan-1-amine (CAS 1393553-78-0)
- 6-(N-(2-cyanoethyl)-N-methylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 317329-41-2)
- Fudosteine Impurity 86 (CAS CATO-C4X-144786)
- {2-[(2-chlorobenzyl)thio]phenyl}amine hydrochloride (CAS 1049739-00-5)
- 4-((2-(5-Chloro-2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)-N-methylnicotinamide (CAS 773138-82-2)
- 5-Bromoquinazolin-4-amine (CAS 1201784-87-3)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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