4-((2-(5-Chloro-2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)-N-methylnicotinamide CAS 773138-82-2
| CAS No. | 773138-82-2 |
| Molecular Formula | C20H17ClFN5O |
| Molecular Weight | 397.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-((2-(5-Chloro-2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)-N-methylnicotinamide (CAS 773138-82-2), a certified reference material (molecular formula C20H17ClFN5O, MW 397.83 g/mol) for analytical method development and quality control.
4-((2-(5-Chloro-2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)-N-methylnicotinamide (C20H17ClFN5O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((2-(5-Chloro-2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)-N-methylnicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H17ClFN5O |
| Molecular Weight | 397.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-{2-[(1E)-{[(2-chloro-4-fluorophenyl)methoxy]imino}methyl]-1H-pyrrol-1-yl}-4-(dimethylamino)pyridine-3-carbonitrile (CAS 303986-45-0)
- 2-Chloro-6-ethoxy-4-formylphenyl 4-acetamidobenzenesulfonate (CAS 432012-07-2)
- Ethyl 3-[(2-chloro-6-fluorobenzyl)oxy]pyrido[1,2-a]indole-10-carboxylate (CAS 478067-96-8)
- 2-(5-(3-Chloro-4-methylphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl)-N-phenylacetamide (CAS 1009200-90-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(4-methylbenzyl) oxime (CAS 250714-07-9)
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one (CAS 339111-39-6)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 297150-41-5)
- N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)formamide (CAS 401637-50-1)
Recommended Standards
- 5-((4-Chlorophenyl)sulfonyl)-N-(4-fluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 338791-91-6)
- 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane (CAS 339276-53-8)
- N-(2-(1H-indol-3-yl)ethyl)-3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 920700-26-1)
- Topramezone Impurity 3 (CAS CATO-C4X-35033)
- N-(2-chloro-4-fluorobenzyl)pyridin-2-amine (CAS 942852-80-4)
- n-Acetyl-N-(p-tolyl)glycine (CAS 119656-41-6)
- H-D-Phe-D-Phe-D-Leu-OH (CAS CATO-CPTD788748)
- 2-(6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1805228-88-9)
- ethyl 2-(dimethoxyphosphoryl)-3,3,3-trifluoro-2-{[(4-methylphenyl)sulphonyl]amino}propanoate (CAS 340033-07-0)
- 1-(Difluoromethoxy)-4-methyl-2-(trifluoromethyl)benzene (CAS 1261862-36-5)
- 2-(5,6-Dimethoxypyridin-2-yl)ethan-1-amine (CAS 1256825-11-2)
- 5-Methyl-2-(methylamino)benzene-1-thiol (CAS 79226-39-4)
- Benzene,1-(1,1-dimethylethyl)-4-(methylthio) (CAS 7252-86-0)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com