2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid CAS 1431729-98-4
| CAS No. | 1431729-98-4 |
| Molecular Formula | C8H4F2N4O2 |
| Molecular Weight | 226.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 226.14 g/mol gives 2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-98-4) is a high-purity analytical reference standard with the molecular formula C8H4F2N4O2 and a molecular weight of 226.14 g/mol.
Based on its molecular formula C8H4F2N4O2, 2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F2N4O2 |
| Molecular Weight | 226.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Difluoropyridin Standards
- (2,6-Difluoropyridin-3-yl)(phenyl)methanone (CAS 1158955-21-5)
- (4-(2,6-Difluoropyridin-3-yl)phenyl)boronic acid (CAS 919288-46-3)
- methyl [(2,6-difluoropyridin-3-yl)carbamoyl]formate (CAS 1803585-80-9)
- 1-(3,5-Difluoropyridin-2-yl)-2,2,2-trifluoroethanamine (CAS 1270394-79-0)
- 1-(2,6-Difluoropyridin-3-yl)-2,2,2-trifluoroethanone (CAS 1707361-89-4)
- ethyl 2-(3,5-difluoropyridin-2-yl)-2,2-difluoroacetate (CAS 1838637-13-0)
- (E)-1-(3,5-Difluoropyridin-2-yl)-2-methoxyethanone oxime (CAS 1075757-31-1)
- Ethyl 2-(3,5-difluoropyridin-2-yl)acetate (CAS 940933-44-8)
Recommended Standards
- 1-Methoxy-4-(perfluoroethyl)benzene (CAS 14038-06-3)
- 3-(3,5-Difluorophenyl)-1,1,1-trifluoropropan-2-ol (CAS 1603473-47-7)
- 5-(2,5-Difluorophenyl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1344306-77-9)
- 2,2-Difluoro-2-(4-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1781189-72-7)
- Aminooxy-PEG3-C2-thiol (CAS 1200365-63-4)
- (Z)-1,5-Octadiene-3-one (CAS 65767-22-8)
- 951887-58-4 2-Chloro-3-[(3,4-ethylenedioxy)phenyl]-1-propene MFCD07782403 (CAS 951887-58-4)
- (4R,5S)-5-(Hydroxymethyl)-3-methyl-4-phenyloxazolidin-2-one (CAS 828272-16-8)
- 2,4-Dichloro-3-(difluoromethoxy)benzenesulfonyl chloride (CAS 1803817-79-9)
- Ceftiofur (CAS 80370-57-6)
- Methyl 2-[(5-Bromo-2-fluorophenyl)amino]-2-cyclopropylacetate (CAS 1967246-40-7)
- Griseofulvin EP Impurity C (CAS 3573-90-8)
- Platinum,dodecakis[2-(2-propenyl)benzenethiolato]hexa- (CAS 39448-24-3)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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