ethyl 2-(3,5-difluoropyridin-2-yl)-2,2-difluoroacetate CAS 1838637-13-0
| CAS No. | 1838637-13-0 |
| Molecular Formula | C9H13F4NO2 |
| Molecular Weight | 243.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
ethyl 2-(3,5-difluoropyridin-2-yl)-2,2-difluoroacetate (CAS 1838637-13-0), molecular formula C9H13F4NO2 and molecular weight 243.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of ethyl 2-(3,5-difluoropyridin-2-yl)-2,2-difluoroacetate (C9H13F4NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H13F4NO2 |
| Molecular Weight | 243.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related ethyl Standards
- (4-(2,6-Difluoropyridin-3-yl)phenyl)boronic acid (CAS 919288-46-3)
- (3-(3,5-Difluoropyridin-2-yl)-4-fluorophenyl)boronic acid (CAS 425379-32-4)
- 2-(3,5-Difluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-98-4)
- 2-((5,6-Difluoropyridin-3-yl)amino)-5-methylbenzoic acid (CAS 1119085-77-6)
- Benzyl (5,6-difluoropyridin-3-yl)carbamate (CAS 2007910-54-3)
- (2,6-Difluoropyridin-3-yl)(phenyl)methanone (CAS 1158955-21-5)
- methyl [(2,6-difluoropyridin-3-yl)carbamoyl]formate (CAS 1803585-80-9)
- 1-(3,5-Difluoropyridin-2-yl)-2,2,2-trifluoroethanamine (CAS 1270394-79-0)
Recommended Standards
- 4-(2,2,2-Trifluoroacetyl)thiomorpholine-3-carboxylic acid (CAS 1543574-08-8)
- [2-(3,5-dichlorophenyl)ethynyl]trimethylsilane (CAS 351865-83-3)
- 2-Methyl-3-(2,2,2-trifluoroacetyl)thiazolidine-4-carboxylic acid (CAS 1339496-78-4)
- 1,1,1-Trifluoro-N-methyl-N-(5-methylfuran-2-yl)methanesulfonamide (CAS 500227-25-8)
- 6-Chloro-2,3-difluoro-4-(trifluoromethyl)benzaldehyde (CAS 914635-34-0)
- trans-N-Methylazetidin-3-amine dihydrochloride (CAS 133891-77-7)
- 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine (CAS 76790-27-7)
- 2-Chloro-4-isobutyl-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1774903-28-4)
- Itopride Impurity 20 (CAS 131028-54-1)
- tert-Butyl 2-(methylthio)-4-(((trifluoromethyl)sulfonyl)oxy)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate (CAS 338739-82-5)
- (R)-(1-methyl-2-tritylisoindolin-5-yl)boronic acid (CAS 223595-19-5)
- 5-Fluoro-2-nitrobenzene-1-sulfonamide (CAS 1247431-23-7)
- Tert-butyl 5-(hydroxymethyl)-7-oxa-2-azaspiro[3.5]Nonane-2-carboxylate (CAS 1357353-23-1)
- (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) trifluoroacetate salt (CAS 2022956-55-2)
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