(3,5-Difluoropyridin-2-yl)boronic acid CAS 1432507-35-1
| CAS No. | 1432507-35-1 |
| Molecular Formula | C5H4BF2NO2 |
| Molecular Weight | 158.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3,5-Difluoropyridin-2-yl)boronic acid (C5H4BF2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(3,5-Difluoropyridin-2-yl)boronic acid (CAS 1432507-35-1) is a high-purity analytical reference standard with the molecular formula C5H4BF2NO2 and a molecular weight of 158.90 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3,5-Difluoropyridin-2-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4BF2NO2 |
| Molecular Weight | 158.90 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropyridin Standards
- (2,4-Difluoropyridin-3-yl)boronic acid (CAS 1353756-61-2)
- (5,6-Difluoropyridin-3-yl)boronic acid (CAS 1366482-40-7)
- (3,5-Difluoropyridin-4-yl)boronic acid (CAS 956003-87-5)
- 2-(3,5-Difluoropyridin-2-yl)ethan-1-ol (CAS 1000506-82-0)
- 1-(3,5-Difluoropyridin-2-yl)ethanol (CAS 1075756-92-1)
- 1-(2,5-Difluoropyridin-3-yl)ethan-1-ol (CAS 1505516-31-3)
- 1-(2,5-Difluoropyridin-4-yl)ethanol (CAS 1784520-98-4)
- (R)-1-(2,5-Difluoropyridin-3-yl)ethanol (CAS 2643926-86-5)
Recommended Standards
- 2,6-Difluoropyridine-4-boronic Acid (CAS 401816-16-8)
- 2,5-Difluoropyridine-4-boronic Acid (CAS 1263375-23-0)
- Tb Standard Solution (CAS 7440-27-9)
- 2,3-Difluoropyridine-4-boronic Acid (CAS 1263374-42-0)
- 3-Chloro-5-isopropoxybenzoic Acid (CAS 1369810-45-6)
- Pcb No. 104 (CAS 56558-16-8)
- N1-(3,5-Dichloropyridin-2-yl)ethane-1,2-diamine (CAS 253309-39-6)
- Pidotimod Impurity 11 (CAS CATO-C4X-107811)
- 4-(Tetrazolo[1,5-b]pyridazin-6-ylamino)cyclohexan-1-ol (CAS 1010530-98-9)
- Capecitabine (CAS 154361-50-9)
- 6-Morpholinopyridine-3-sulfonamide (CAS 90648-77-4)
- 2,4-Dichloro-1-iodobenzene (CAS 29898-32-6)
- Hydrocortisone Impurity 24 (CAS CATO-C4X-140124)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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