tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate CAS 143306-64-3
| CAS No. | 143306-64-3 |
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate (CAS 143306-64-3) is a high-purity analytical reference standard with the molecular formula C12H19NO3 and a molecular weight of 225.28 g/mol.
The molecular framework of tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate (C12H19NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 7-(2-Fluorophenyl)-1,4-thiazepan-5-one (CAS 1428234-41-6)
- tert-butyl 2-oxo-5-azaspiro[3.4]octane-5-carboxylate (CAS 1434141-78-2)
- tert-Butyl 7-oxo-3-azabicyclo[4.2.0]octane-3-carboxylate (CAS 1427358-74-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com