4-Hydroxy-3,3-dimethyl-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester CAS 143306-65-4
| CAS No. | 143306-65-4 |
| Molecular Formula | C12H23NO3 |
| Molecular Weight | 229.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-3,3-dimethyl-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester (C12H23NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-Hydroxy-3,3-dimethyl-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester (CAS 143306-65-4) is a high-purity analytical reference standard with the molecular formula C12H23NO3 and a molecular weight of 229.32 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H23NO3 |
| Molecular Weight | 229.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 1-Boc-4-hydroxy-2,2-dimethylpiperidine (CAS 1502162-73-3)
- cis-(4-hydroxy-cyclohexyl)-methyl-carbamic acid tert-butyl ester (CAS 561307-54-8)
- N-(4-Hydroxy-3-isopropylphenyl)methanesulfonamide (CAS 1243279-78-8)
- N-(5-Hydroxy-2-isopropylphenyl)methanesulfonamide (CAS 1243280-00-3)
- N-(4-Hydroxy-2-isopropylphenyl)methanesulfonamide (CAS 1243328-35-9)
- N-(3-Hydroxy-5-isopropylphenyl)methanesulfonamide (CAS 1243373-37-6)
- N-(2-Hydroxy-6-isopropylphenyl)methanesulfonamide (CAS 1243386-79-9)
- N-(3-Hydroxy-4-isopropylphenyl)methanesulfonamide (CAS 1243451-80-0)
Recommended Standards
- N-Decanoylglycine (CAS 14305-32-9)
- 1-((1H-benzo[d]imidazol-2-yl)methyl)cyclohexan-1-amine (CAS 1435804-82-2)
- Tert-butyl 3-hydroxy-3-isobutylazetidine-1-carboxylate (CAS 1428901-14-7)
- 1-(4-Propylphenyl)-1-(1H-pyrrol-2-yl)ethanol (CAS 1443307-02-5)
- O1-tert-butyl O3-methyl (3R,6R)-6-methylpiperazine-1,3-dicarboxylate (CAS 2349395-78-2)
- 4-(2,4-Dimethylphenyl)thiazol-2-amine (CAS 247225-31-6)
- 2-(tributylstannyl)-3-(trifluoromethyl)pyridine, 95% (CAS 1204580-78-8)
- 6-Chloro-3-(2-(1-(ethylthio)cyclopropyl)phenoxy)pyridazin-4-ol (CAS 499223-34-6)
- 3-Chloro-4-[(2,4-dichlorobenzyl)oxy]benzaldehyde (CAS 433242-78-5)
- (R)-1-(3-Methoxyphenyl)propan-1-amine hydrochloride (CAS 856562-95-3)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid (CAS 1260382-42-0)
- Bedaquiline Impurity 26 (CAS 654654-19-0)
- (2-Chloro-5-methylthiazol-4-yl)methanamine (CAS 1379350-69-2)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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