Apixaban Impurity 17 CAS 1434050-55-1
| CAS No. | 1434050-55-1 |
| Molecular Formula | C18H18ClN3O2 |
| Molecular Weight | 343.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 343.81 g/mol gives Apixaban Impurity 17 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Apixaban Impurity 17 (CAS 1434050-55-1), a certified reference material (molecular formula C18H18ClN3O2, MW 343.81 g/mol) for analytical method development and quality control.
The molecular framework of Apixaban Impurity 17 (C18H18ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Apixaban Impurity 17 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O2 |
| Molecular Weight | 343.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Apixaban Standards
- Apixaban Impurity 122 (CAS CATO-C4X-1088122)
- Apixaban Impurity N3 (CAS 2413365-22-5)
- Apixaban Impurity 25 (CAS CATO-C4X-108825)
- Apixaban Impurity 33 (CAS 545445-44-1)
- Apixaban Impurity 168 (CAS CATO-C4X-1088168)
- Apixaban Impurity 78 (CAS CATO-C4X-108878)
- Apixaban Impurity 89 (CAS CATO-C4X-108889)
- Apixaban Impurity 23 (CAS CATO-C4X-108823)
Recommended Standards
- N-(1-acetyl-3,3-dimethylindolin-6-yl)-2-chloronicotinamide (CAS 1420999-91-2)
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- 3-(3-Chlorophenyl)-5-(3,4-diethoxyphenyl)-1H-1,2,4-triazole (CAS 1416346-61-6)
- 2-([1,1'-Biphenyl]-4-yl)-4-chloro-6-phenyl-1,3,5-triazine (CAS 1472062-94-4)
- (1-(2,5-Dimethylbenzyl)cyclopropyl)methanol (CAS 1485339-57-8)
- Benzo[h]quinolin-10(1H)-one (CAS 142506-60-3)
- Ethyl 4-methoxy-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 214360-61-9)
- 4-(4,5-Dihydro-1,3-thiazol-2-ylsulfanyl)butan-1-amine (CAS 642092-90-8)
- 3-Bromo-N-isopropyl-5-(trifluoromethyl)aniline (CAS 1396779-98-8)
- 5-Phenylfuran-2(3H)-one (CAS 1955-39-1)
- 3-Oxo-2,3-dihydro-1H-indene-5-carbaldehyde (CAS 1187243-14-6)
- 5-Ethyl-3-(3-nitrophenyl)isoxazole (CAS 449181-21-9)
- 4'-(Methylsulfonyl)[1,1'-biphenyl]-3-carbonitrile (CAS 893738-72-2)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com