Apixaban Impurity 168 CAS CATO-C4X-1088168
| CAS No. | CATO-C4X-1088168 |
| Molecular Formula | C16H20Cl2N2O3 |
| Molecular Weight | 359.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apixaban Impurity 168 (CAS CATO-C4X-1088168) is a certified pharmaceutical impurity reference standard with the molecular formula C16H20Cl2N2O3 and a molecular weight of 359.25 g/mol.
Based on its molecular formula C16H20Cl2N2O3, Apixaban Impurity 168 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 359.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apixaban Impurity 168 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20Cl2N2O3 |
| Molecular Weight | 359.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Apixaban Standards
- Apixaban Impurity 78 (CAS CATO-C4X-108878)
- Apixaban Impurity 33 (CAS 545445-44-1)
- Apixaban Impurity N3 (CAS 2413365-22-5)
- Apixaban Impurity 25 (CAS CATO-C4X-108825)
- Apixaban Impurity 123 (CAS CATO-C4X-1088123)
- Apixaban Impurity 16 (CAS 2098457-93-1)
- Apixaban Impurity 30 (CAS 1686149-78-9)
- Apixaban Impurity 15 (CAS CATO-C4X-108815)
Recommended Standards
- Linezolid Impurity 66 (CAS CATO-C4X-107366)
- Pyrimethamine Impurity 4 (CAS CATO-C4X-20444)
- Pentafluorophenyl 2-pyrrolidin-1-ylpyrimidine-5-carboxylate (CAS 946409-38-7)
- 1-(4-Bromophenyl)-4-phenylnaphthalene (CAS 1170321-08-0)
- Indobufen Impurity 32 (CAS 21762-24-3)
- Valaciclovir Impurity 43 (CAS CATO-C4X-124843)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- (4-((2-Ethylhexyl)oxy)-2,5-dimethylphenyl)boronic acid (CAS 409359-66-6)
- Ethyl 2-(1-methylpiperidin-4-yl)pyrimidine-5-carboxylate (CAS 1447607-67-1)
- (4-((3-Methylpiperidin-1-yl)methyl)phenyl)methanamine (CAS 923137-50-2)
- 4′-Methoxy[1,1′-biphenyl]-3-amine (CAS 53059-28-2)
- 5-iodo-2,3-dihydrobenzo[b]furan (CAS 132464-84-7)
- 3-(Pyrrolidin-1-yl)butanoic acid hydrochloride (CAS 237062-38-3)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com