5-Fluoro-3-(3-hydroxypropyl)-2-(methylthio)pyrimidin-4(3H)-one CAS 143612-39-9

Description

5-Fluoro-3-(3-hydroxypropyl)-2-(methylthio)pyrimidin-4(3H)-one (CAS 143612-39-9), molecular formula C8H11FN2O2S and molecular weight 218.25 g/mol, is a CATO reference standard with documented purity and traceability.

5-Fluoro-3-(3-hydroxypropyl)-2-(methylthio)pyrimidin-4(3H)-one (C8H11FN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Fluoro-3-(3-hydroxypropyl)-2-(methylthio)pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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