Ethyl 3-Chloro-6-iodopyridine-2-carboxylate CAS 1436504-90-3
| CAS No. | 1436504-90-3 |
| Molecular Formula | C8H7ClINO2 |
| Molecular Weight | 311.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-Chloro-6-iodopyridine-2-carboxylate.
Ethyl 3-Chloro-6-iodopyridine-2-carboxylate (CAS 1436504-90-3) is a high-purity analytical reference standard with the molecular formula C8H7ClINO2 and a molecular weight of 311.50 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, Ethyl 3-Chloro-6-iodopyridine-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 3-Chloro-6-iodopyridine-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClINO2 |
| Molecular Weight | 311.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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- Methyl 6-chloro-2-iodo-5-methylnicotinate (CAS 1043870-59-2)
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- 1-(5-Bromopyridin-3-yl)ethan-1-amine (CAS 886374-05-6)
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- 2-(4-Benzyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-6-phenyl-3,4-dihydropyrimidin-4-one (CAS 866137-81-7)
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