Ethyl 6-chloro-5-iodonicotinate CAS 856166-01-3
| CAS No. | 856166-01-3 |
| Molecular Formula | C8H7ClINO2 |
| Molecular Weight | 311.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 311.50 g/mol gives Ethyl 6-chloro-5-iodonicotinate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 6-chloro-5-iodonicotinate (CAS 856166-01-3), molecular formula C8H7ClINO2 and molecular weight 311.50 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 6-chloro-5-iodonicotinate (C8H7ClINO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 311.50 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 6-chloro-5-iodonicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClINO2 |
| Molecular Weight | 311.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-chloro-3-iodoisonicotinate (CAS 1034132-14-3)
- Methyl 6-chloro-2-iodo-5-methylnicotinate (CAS 1043870-59-2)
- Ethyl 3-Chloro-6-iodopyridine-2-carboxylate (CAS 1436504-90-3)
- Methyl 6-chloro-5-iodo-2-methylnicotinate (CAS 1710661-18-9)
- 2-Chloro-3-(1,3-dioxolan-2-yl)-4-iodopyridine (CAS 2586127-42-4)
- 2-Chloro-5-iodo-4,6-dimethylpyridine-3-carboxylic acid (CAS 2197057-50-2)
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Recommended Standards
- Methyl 2-amino-4-chloro-5-iodobenzoate (CAS 199850-56-1)
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- Methyl 2-amino-5-chloro-3-iodobenzoate (CAS 289039-84-5)
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- 3-Chloro-4-[(2,4-dichlorobenzyl)oxy]benzaldehyde (CAS 433242-78-5)
- N-(2-Ethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483995-87-5)
- 4-(1-Ethyl-1h-1,2,4-triazol-5-yl)butanoic acid (CAS 1248252-24-5)
- 2-Amino-1-(5-(trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 1211529-78-0)
- Dimethyl Hexanedioate-3,3,4,4-d4 (CAS 55724-08-8)
- Articaine impurity 20 (CAS CATO-C4X-191220)
- Metronidazole Impurity 15 (CAS 110578-73-9)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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