1-(6-Fluoro-4-methylquinolin-2-yl)propan-2-one CAS 1437458-12-2
| CAS No. | 1437458-12-2 |
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(6-Fluoro-4-methylquinolin-2-yl)propan-2-one.
CATO supplies 1-(6-Fluoro-4-methylquinolin-2-yl)propan-2-one (CAS 1437458-12-2), a certified reference material (molecular formula C13H12FNO, MW 217.24 g/mol) for analytical method development and quality control.
1-(6-Fluoro-4-methylquinolin-2-yl)propan-2-one (C13H12FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-amine (CAS 1048915-78-1)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-amine (CAS 1182804-44-9)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-amine (CAS 1184082-67-4)
- 4'-Fluoro-4-methoxy-[1,1'-biphenyl]-3-amine (CAS 1214367-37-9)
- 4-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-amine (CAS 1225961-50-1)
- 6-Fluoro-N-((3-methylpyridin-2-yl)methyl)pyridin-2-amine (CAS 1333514-25-2)
- (4-Fluoro-2-methylphenyl)(pyridin-2-yl)methanol (CAS 1339194-11-4)
- (4-Fluoro-3-methylphenyl)(pyridin-2-yl)methanol (CAS 1340029-13-1)
Recommended Standards
- 2-Ammonio-2-phenylethyl sulfate (CAS 1437-78-1)
- 1-(8-Fluoro-4-methylquinolin-2-yl)propan-2-one (CAS 1437480-09-5)
- 3-(2-Fluorophenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 1416440-66-8)
- 3-(Benzyloxy)-5-fluoroaniline (CAS 1438272-88-8)
- N-(1-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-methylprop-1-en-1-yl)-N-methylaniline (CAS 305861-35-2)
- (R)-2-((Methylsulfonyl)methyl)morpholine (CAS 2791475-60-8)
- 2-(Morpholinomethyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 20887-01-8)
- Isoxathion (CAS 18854-01-8)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-[(2E)-2-[(4-methoxyphenyl)imino]ethyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303148-40-5)
- 2,5-Dibromo-3-methoxythiophene (CAS 148078-36-8)
- (E)-1-butyl-4,5-diphenyl-2-((3-(trifluoromethyl)benzylidene)amino)-1H-pyrrole-3-carbonitrile (CAS 478032-83-6)
- Thiopropazate Dihydrochloride (CAS 146-28-1)
- 1-(5-Bromo-3-pyridinyl)-1-pentanone (CAS 856886-61-8)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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