4-[4,4-Dimethyl-3-(2-hydroxyethyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile CAS 143782-37-0
| CAS No. | 143782-37-0 |
| Molecular Formula | C15H14F3N3O2S |
| Molecular Weight | 357.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-[4,4-Dimethyl-3-(2-hydroxyethyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile (CAS 143782-37-0), molecular formula C15H14F3N3O2S and molecular weight 357.35 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[4,4-Dimethyl-3-(2-hydroxyethyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile (C15H14F3N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 4-[4,4-Dimethyl-3-(2-hydroxyethyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14F3N3O2S |
| Molecular Weight | 357.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (1R,5S)-tert-Butyl 3-(((trifluoromethyl)sulfonyl)oxy)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylate (CAS 1245646-51-8)
- Tert-butyl 3-(((trifluoromethyl)sulfonyl)oxy)-8-azabicyclo[3.2.1]Oct-2-ene-8-carboxylate (CAS 185099-68-7)
- Trametinib impurity 11 (CAS CATO-C4X-278211)
- tert-Butyl 7-(((trifluoromethyl)sulfonyl)oxy)-4-azaspiro[2.5]oct-6-ene-4-carboxylate (CAS 1892578-22-1)
- Methyl 2-methyl-5-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 1313752-95-2)
- (R)-2-(1-nitronaphthalen-2-yl)pyrrolidine (CAS 1334911-22-6)
- Kamebakaurin (CAS 73981-34-7)
- 2-Methyl-1H-pyrrolo[2,3-d]pyrimidin-6(5H)-one (CAS 118801-71-1)
- tert-Butyl 4-(5-benzoyl-4-methylpyridin-2-yl)piperazine-1-carboxylate (CAS 1355196-00-7)
- 3-Bromo-6-(2-methoxyphenyl)pyridine (CAS 1194683-55-0)
- [4'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl] acetonitrile (CAS 893737-90-1)
- (2-(4-Chloro-2-methylphenoxy)pyridin-3-yl)(4-(2-fluorophenyl)piperazin-1-yl)methanone (CAS 497060-65-8)
- 6-(4-Bromophenyl)-4-phenyl-4,5-dihydropyridazin-3(2H)-one (CAS 344282-67-3)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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