4-Amino-2-chloro-6-methylpyrimidine CAS 14394-60-6
| CAS No. | 14394-60-6 |
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Amino-2-chloro-6-methylpyrimidine (CAS 14394-60-6), a certified reference material (molecular formula C5H6ClN3, MW 143.57 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-2-chloro-6-methylpyrimidine (C5H6ClN3) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-2-chloro-6-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-5-(chloromethyl)pyrimidine Hydrochloride (CAS 120747-86-6)
- 4-Amino-2-chloro-5-methylpyrimidine, Technical grade >80% (CAS 14394-70-8)
- 2-Amino-3-chloro-6-methylpyrazine (CAS 89182-15-0)
- 2-Amino-6-chlorophenol (CAS 38191-33-2)
- 3-Amino-5-chlorophenol (CAS 883195-40-2)
- 3-Amino-6-chloro-4-methylpyridazine (CAS 64068-00-4)
- 5-Amino-2-chloro-4-methylpyrimidine (CAS 20090-69-1)
- 5-Amino-4-chloro-2-methylpyrimidine (CAS 20090-59-9)
Recommended Standards
- 6-chloro-5-methylpyrimidin-4-amine (CAS 14394-56-0)
- 2-Chloro-5-methoxypyridine (CAS 139585-48-1)
- 2-Chloro-5-hydrazinylpyridine (CAS 145934-89-0)
- 5-Chloro-2-methoxypyridine (CAS 13473-01-3)
- 2-(3-aminoazetidin-1-yl)ethan-1-ol (CAS 1409292-18-7)
- 4-Bromo-2-ethoxy-6-methylpyridine (CAS 1300633-96-8)
- (E)-3-(4-chloro-3,5-difluorophenyl)acrylic acid (CAS 1163258-83-0)
- O6-Benzylguanine (CAS 19916-73-5)
- 2-[2-(Methylsulfanyl)phenyl]-5-phenyl-1,3,4-oxadiazole (CAS 339014-15-2)
- 1-(4-Methylpyridin-2-yl)piperidin-4-amine hydrochloride (CAS 1185308-02-4)
- THP-SS-alcohol (CAS 877864-04-5)
- 53916-94-2 2-Phenylethylamine hydrobromide MFCD29089369 (CAS 53916-94-2)
- (S,S)-3-Methyl-3,6-diaza-bicyclo[3.2.0]heptane (CAS 1419075-95-8)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
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