3-Amino-6-chloro-4-methylpyridazine CAS 64068-00-4
| CAS No. | 64068-00-4 |
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 143.57 g/mol gives 3-Amino-6-chloro-4-methylpyridazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Amino-6-chloro-4-methylpyridazine (CAS 64068-00-4) is a high-purity analytical reference standard with the molecular formula C5H6ClN3 and a molecular weight of 143.57 g/mol.
The molecular framework of 3-Amino-6-chloro-4-methylpyridazine (C5H6ClN3) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-6-chloro-4-methylpyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-5-(chloromethyl)pyrimidine Hydrochloride (CAS 120747-86-6)
- 4-Amino-2-chloro-6-methylpyrimidine (CAS 14394-60-6)
- 4-Amino-2-chloro-5-methylpyrimidine, Technical grade >80% (CAS 14394-70-8)
- 2-Amino-3-chloro-6-methylpyrazine (CAS 89182-15-0)
- 2-Amino-6-chlorophenol (CAS 38191-33-2)
- 3-Amino-5-chlorophenol (CAS 883195-40-2)
- 5-Amino-2-chloro-4-methylpyrimidine (CAS 20090-69-1)
- 5-Amino-4-chloro-2-methylpyrimidine (CAS 20090-59-9)
Recommended Standards
- 3-Chloro-1-methylpyridin-4(1h)-one (CAS 857201-58-2)
- 2-Chloropyridine-3,5-diamine (CAS 5632-81-5)
- 3-Chloro-2,6-pyridinediamine (CAS 54903-85-4)
- 2-Chloro-N-methylpyrimidin-4-amine (CAS 66131-68-8)
- 5-((tert-Butoxycarbonyl)amino)-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxylic acid (CAS 2177263-49-7)
- Ethyl 5-fluoro-2-nitrobenzoate (CAS 364-51-2)
- 5'-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-4,4-dimethyl-hexahydrospiro[cyclohexane-1,3'-pyrrolo[3,4-d][1,2]oxazole]-2,4',6,6'-tetrone (CAS 338772-51-3)
- 8-Aminochroman-4-one (CAS 1260018-33-4)
- Tert-butyl (2-fluorobenzyl)carbamate (CAS 153903-21-0)
- 4-(Methylsulfanyl)-2-oxo-6-phenyl-1-(prop-2-en-1-yl)-1,2-dihydropyridine-3-carbonitrile (CAS 478042-85-2)
- 3-(1H-pyrazol-1-yl)piperidine (CAS 1211541-73-9)
- 4-Amino-3-methyl-2-(3-methylthiophen-2-yl)butan-2-ol (CAS 1513708-89-8)
- 5-Chloro-6-fluoropyridin-3-amine (CAS 1256790-26-7)
- Peptide 442 (CAS CATO-CPTD788442)
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