Ritonavir Impurity 30 CAS 144164-11-4
| CAS No. | 144164-11-4 |
| Molecular Formula | C23H27N3O3S |
| Molecular Weight | 425.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ritonavir Impurity 30 (CAS 144164-11-4) is a certified pharmaceutical impurity reference standard with the molecular formula C23H27N3O3S and a molecular weight of 425.54 g/mol.
Structurally, Ritonavir Impurity 30 (C23H27N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 425.54 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27N3O3S |
| Molecular Weight | 425.54 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ritonavir Standards
- Ritonavir Impurity 55 (CAS CATO-C4X-175155)
- Ritonavir Impurity 62 (CAS CATO-C4X-175162)
- Ritonavir Impurity 60 (CAS 2454100-44-6)
- Ritonavir Impurity 32 (CAS CATO-C4X-175132)
- Ritonavir Impurity 34 (CAS CATO-C4X-175134)
- Ritonavir Impurity 35 (CAS 144163-85-9)
- Ritonavir EP Impurity C (CAS 1010808-43-1)
- Ritonavir EP Impurity M (CAS CATO-C4X-175114)
Recommended Standards
- Quetiapine EP Impurity A (CAS 844639-07-2)
- Efinaconazole Impurity 25 (CAS 2055912-03-1)
- (R)-2,3-Bis(hexyloxy)propyl (2-(trimethylammonio)ethyl) phosphate 79645-39-9 (CAS 79645-39-9)
- Indocyanine Green Impurity 43 (CAS CATO-C4X-250343)
- Elagolix Impurity 118 (CAS CATO-C4X-2068118)
- Glibenclamide Impurity 6 (CAS 33924-49-1)
- Molnupiravir Impurity 16 (CAS CATO-C4X-249016)
- Methyl 3-(3-bromophenyl)-2-propenoate (CAS 3650-77-9)
- 3-(Ethylsulfanyl)propanoic acid (CAS 7244-82-8)
- Peramivir impurity 141 (CAS CATO-C4X-1833141)
- 1,3,4-Oxadiazol-2(3H)-one, 5-(1-methylethyl)-5-(propan-2-yl)-2,3-dihydro-1,3,4-oxadiazol-2-one (CAS 1711-88-2)
- N-((5-Fluoro-1,3-dimethyl-1H-pyrazol-4-yl)methyl)-2-morpholinoethan-1-amine hydrochloride (CAS 1856066-44-8)
- 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 537017-56-4)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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