Glibenclamide Impurity 6 CAS 33924-49-1
| CAS No. | 33924-49-1 |
| Molecular Formula | C16H16ClNO2 |
| Molecular Weight | 289.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Glibenclamide Impurity 6.
As a process- or degradation-related impurity, Glibenclamide Impurity 6 (CAS 33924-49-1, C16H16ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Glibenclamide Impurity 6 (C16H16ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 289.76 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Glibenclamide Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO2 |
| Molecular Weight | 289.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Glibenclamide Standards
- Glibenclamide EP Impurity A (CAS 16673-34-0)
- Glibenclamide Impurity 7 (CAS 3438-16-2)
- Glibenclamide EP Impurity B (CAS 21165-77-5)
- Glibenclamide EP Impurity D (CAS 38160-73-5)
- Glibenclamide (CAS 10238-21-8)
- Glibenclamide trans-4-Hydroxycyclohexyl (CAS 23155-00-2)
- Glibenclamide EP Impurity E (CAS 57334-89-1)
Recommended Standards
- Dexchlorpheniramine Impurity 6 (CAS CATO-C4X-16116)
- Lifitegrast Impurity 142 (CAS 2098810-32-1)
- N-Nitrosodemethyl Chlorphenamine (CAS CATO-C4X-118834)
- Coumarin 102 Impurity 5 (CAS CATO-C4X-24335)
- Relmapirazin impurity 12 (CAS CATO-C4X-333412)
- Daclatasvir Impurity 32 (CAS 1009107-27-0)
- Bumetanide Impurity 8 (CAS 25317-76-4)
- Hydroxychloroquine Impurity 31 (CAS CATO-C4X-183531)
- Metabromsalon (CAS 2577-72-2)
- (R)-2-Amino-2-(5-bromopyridin-2-yl)ethan-1-ol dihydrochloride (CAS 2126088-18-2)
- N-(3-nitrophenyl)ethanediamide (CAS 861332-65-2)
- Dihydroxy(stearoyloxy)aluminum (CAS 7047-84-9)
- 2-Chloro-5-isobutyl-1,3,4-thiadiazole (CAS 99420-56-1)
- Peptide 440 (CAS CATO-CPTD788440)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com