Ripretinib Impurity 2 CAS 1442470-53-2
| CAS No. | 1442470-53-2 |
| Molecular Formula | C17H16BrFN4O |
| Molecular Weight | 391.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ripretinib Impurity 2 (C17H16BrFN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Ripretinib Impurity 2 (CAS 1442470-53-2) is a certified pharmaceutical impurity reference standard with the molecular formula C17H16BrFN4O and a molecular weight of 391.24 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ripretinib Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16BrFN4O |
| Molecular Weight | 391.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
Related Ripretinib Standards
Recommended Standards
- Platinum,[ethanedioato(2-)-O,O'](2-pyridinemethanamine-N1,N2)-,(SP-4-3)- (CAS 93252-13-2)
- 5,7-Dichloro-N-(4-methoxyphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000575-54-1)
- 3-(5-Bromothiophen-2-yl)-N'-(3-hydroxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 303104-92-9)
- 1-(2,6-Dichlorobenzyl)-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 1015939-98-6)
- Salbutamol Impurity 178 (CAS CATO-C4X-1176178)
- Cefdinir Impurity 24 (CAS CATO-C4X-121024)
- N-Ethylcarbazole Impurity 1 (CAS 1088098-21-8)
- Rosiglitazone Impurity 5 (CAS CATO-C4X-21795)
- (2Z,4E)-Octa-2,4-dien-1-ol (CAS 119518-99-9)
- Lodoxamide impurity 23 (CAS CATO-C4X-294923)
- (5-((Dimethylamino)methyl)furan-2-yl)methanol oxalate (CAS 94108-18-6)
- 1-Nitro-4-[(1s,4r)-4-ethylcyclohexyl]benzene (CAS 1881275-95-1)
- 3,5-Bis((tert-butoxycarbonyl)amino)benzoic acid (CAS 133887-83-9)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com