Rosiglitazone Impurity 5 CAS CATO-C4X-21795
| CAS No. | CATO-C4X-21795 |
| Molecular Formula | C20H26N3O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Rosiglitazone Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Rosiglitazone Impurity 5 (CAS CATO-C4X-21795, C20H26N3OCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Rosiglitazone Impurity 5 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 359.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H26N3O Cl |
| Molecular Weight | 359.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rosiglitazone Standards
- Rosiglitazone-d3 (CAS 1132641-22-5)
- Rosiglitazone (CAS 122320-73-4)
- Rosiglitazone Maleate (CAS 155141-29-0)
- Rosiglitazone Impurity 2 (CAS 1797979-55-5)
- Rosiglitazone Impurity 3 (CAS 2142519-15-9)
- Rosiglitazone Sodium (CAS 316371-83-2)
- Rosiglitazone potassium salt (CAS 316371-84-3)
- Rosiglitazone Impurity (5-[4-N-(2-Pyridylamino)ethoxy]benzylidene] thiazolidine-2,4-dione) (CAS 643764-88-9)
Recommended Standards
- Pitolisant impurity 10 (CAS CATO-C4X-252010)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
- Cholic Acid Impurity 85 (CAS CATO-C4X-116085)
- (2-Aminothiazol-5-yl)(p-tolyl)methanone (CAS 27053-22-1)
- 6-Azaspiro[2.5]octan-8-one (CAS 1408278-17-0)
- (3-Fluorophenyl)(cis-hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)methanone (CAS 1218128-87-0)
- (1-(4-(Trifluoromethyl)benzyl)-1h-imidazol-5-yl)methanamine hydrochloride (CAS 1779124-88-7)
- 1-(Chloromethyl)-2-fluoro-4-methoxy-5-nitrobenzene (CAS 2092529-70-7)
- 1-Chloro-7-naphthol (CAS 29921-50-4)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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