Landiolol Impurity 1 CAS 144256-11-1
| CAS No. | 144256-11-1 |
| Molecular Formula | C15H20O5 |
| Molecular Weight | 280.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 280.32 g/mol gives Landiolol Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Landiolol Impurity 1 (CAS 144256-11-1) is a certified pharmaceutical impurity reference standard with the molecular formula C15H20O5 and a molecular weight of 280.32 g/mol.
The molecular framework of Landiolol Impurity 1 (C15H20O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H20O5 |
| Molecular Weight | 280.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related Landiolol Standards
- Landiolol Impurity 12 (CAS 2180628-04-8)
- Landiolol Impurity 124 (CAS CATO-C4X-2621124)
- Landiolol Impurity 142 (CAS CATO-C4X-2621142)
- Landiolol Impurity 92 (CAS CATO-C4X-262192)
- Landiolol Impurity 109 (CAS CATO-C4X-2621109)
- Landiolol Impurity 140 (CAS CATO-C4X-2621140)
- Landiolol Impurity 57 (CAS CATO-C4X-262157)
- Landiolol Impurity 108 (CAS CATO-C4X-2621108)
Recommended Standards
- Carbidopa Impurity 14 (CAS CATO-C4X-231014)
- Benzbromarone Impurity 32 (CAS CATO-C4X-225032)
- Benzbromarone Impurity 25 (CAS CATO-C4X-225025)
- Benzbromarone Impurity 24 (CAS 342415-01-4)
- Atrasentan Impurity 38 (CAS 178607-92-6)
- Dydrogesterone Impurity 4 (CAS 4243-74-7)
- Lenalidomide Impurity 50 (CAS CATO-C4X-190350)
- 2-Azaspiro[4.5]Decane-3-carboxylic acid (CAS 94061-90-2)
- Diethyl 2-(((4-(methoxycarbonyl)thiophen-3-yl)amino)methylene)malonate (CAS 124555-03-9)
- 2-Methyl-N-(6-morpholinopyridin-3-yl)benzamide (CAS 383146-21-2)
- Purmorphamine (CAS 483367-10-8)
- 2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene (CAS 1027231-61-3)
- 1,1'-(9H-Fluorene-2,7-diyl)diethanone (CAS 39665-89-9)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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