Ethyl 3,4-difluorobenzoate CAS 144267-96-9
| CAS No. | 144267-96-9 |
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 3,4-difluorobenzoate (CAS 144267-96-9) is a high-purity analytical reference standard with the molecular formula C9H8F2O2 and a molecular weight of 186.16 g/mol.
Ethyl 3,4-difluorobenzoate (C9H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ethyl 3,4-difluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Ethyl Standards
- Ethyl 2,4-Difluorobenzoate (CAS 108928-00-3)
- Ethyl 2,6-Difluorobenzoate (CAS 19064-14-3)
- Ethyl 2,3-difluorobenzoate (CAS 773134-65-9)
- Ethyl 2,5-Difluorobenzoate (CAS 708-25-8)
- Ethyl 3,5-difluorobenzoate (CAS 350-19-6)
- Sodium 2,5-difluorobenzoate (CAS 522651-42-9)
- Sodium 3,5-difluorobenzoate (CAS 530141-39-0)
- Methyl 2,4-difluorobenzoate (CAS 106614-28-2)
Recommended Standards
- 3,5-Difluoro-4-methylbenzohydrazide (CAS 1429903-99-0)
- (S)-2-((3,4-Difluorophenoxy)methyl)oxirane (CAS 144574-27-6)
- 2,2-Difluoro-3-phenylpropanoic acid (CAS 142977-64-8)
- 2-(Difluoromethoxy)-5-methylbenzaldehyde (CAS 147249-30-7)
- 3-Methoxy-4-[2-oxo-2-(pyrrolidin-1-yl)ethoxy]benzaldehyde (CAS 760183-53-7)
- Ethyl 5-amino-6-chloropyrimidine-4-carboxylate (CAS 1393570-78-9)
- 4-Bromo-5-fluoro-2-iodobenzoic acid (CAS 1870155-80-8)
- (E)-3-(3-(Trifluoromethyl)phenyl)prop-2-en-1-amine (CAS 1315377-88-8)
- 2-Amino-1-((S)-3-((cyclopropylmethyl)amino)piperidin-1-yl)propan-1-one (CAS 1354028-39-9)
- N'-(2-(1H-Imidazol-1-yl)acetyl)-2-chloroacetohydrazide (CAS 1707372-59-5)
- 4-Methoxy-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 192869-82-2)
- Aluminum Zirconium Trichlorohydrex Gly (CAS 134375-99-8)
- (4-Chlorophenyl)(4-methylphenyl)methanamine (CAS 1019462-07-7)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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