2-(4-(4-Fluorophenyl)-2-(pyrrolidin-1-yl)thiazol-5-yl)acetic acid CAS 1443291-75-5
| CAS No. | 1443291-75-5 |
| Molecular Formula | C15H15FN2O2S |
| Molecular Weight | 306.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-(4-Fluorophenyl)-2-(pyrrolidin-1-yl)thiazol-5-yl)acetic acid (CAS 1443291-75-5) is a high-purity analytical reference standard with the molecular formula C15H15FN2O2S and a molecular weight of 306.36 g/mol.
The molecular framework of 2-(4-(4-Fluorophenyl)-2-(pyrrolidin-1-yl)thiazol-5-yl)acetic acid (C15H15FN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-(4-Fluorophenyl)-2-(pyrrolidin-1-yl)thiazol-5-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H15FN2O2S |
| Molecular Weight | 306.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- N-(4-Fluorophenyl)-5-piperidin-3-yl-1,3,4-thiadiazole-2-carboxamide (CAS 1217862-52-6)
- N-(2-Fluorophenyl)-5-piperidin-4-yl-1,3,4-thiadiazole-2-carboxamide (CAS 1217862-72-0)
- (Z)-3-(4-fluorophenyl)-2-(4-phenylthiazol-2-yl)acrylonitrile (CAS 298219-21-3)
- [(3-Fluorophenyl)methoxy][(E)-2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]ethenyl]amine (CAS 338399-64-7)
- 1-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-7-amine (CAS 927996-70-1)
- 1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid (CAS 381193-57-3)
- 2-((4-Fluorophenyl)thio)-6-phenylnicotinonitrile (CAS 252058-88-1)
- 2-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-phenylacrylonitrile (CAS 72740-57-9)
Recommended Standards
- 11-Methyl-3-(5-methyl-2-furyl)-2,3,4,5-tetrahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 1428139-40-5)
- tert-Butyl 4-(4-formyl-3-hydroxyphenyl)piperazine-1-carboxylate, 97% (CAS 1446332-69-9)
- N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-2-phenylbutanamide (CAS 1421491-36-2)
- 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene (CAS 147253-67-6)
- (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (CAS 337928-55-9)
- 5-Amino-6-fluoro-8-methylquinoline-2-carboxylic acid (CAS 1420792-51-3)
- N-(2-(N-(2-(Cyclohex-1-en-1-yl)ethyl)sulfamoyl)ethyl)benzamide (CAS 899956-00-4)
- N1-(5-Chloro-2-methoxyphenyl)-N2-cyclopentyloxalamide (CAS 941999-57-1)
- 2-(3-Cyclopentyl-4-oxo-3,4-dihydrophthalazin-1-yl)propanoic acid (CAS 1344687-99-5)
- 3-(1H-1,2,3-Triazol-1-yl)propanoic acid hydrochloride (CAS 1803604-38-7)
- Opicapone Impurity 54 (CAS CATO-C4X-240454)
- (S)-2-(((Benzyloxy)carbonyl)amino)-5-((diphenyl(p-tolyl)methyl)amino)-5-oxopentanoic acid (CAS 144317-19-1)
- (5-(N,N-Diethylsulfamoyl)-2-fluoro-4-methylphenyl)boronic acid (CAS 1704121-33-4)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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