(3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one CAS 337928-55-9
| CAS No. | 337928-55-9 |
| Molecular Formula | C21H12ClF3N2O3 |
| Molecular Weight | 432.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 432.78 g/mol gives (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (CAS 337928-55-9), a certified reference material (molecular formula C21H12ClF3N2O3, MW 432.78 g/mol) for analytical method development and quality control.
Structurally, (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (C21H12ClF3N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 432.78 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H12ClF3N2O3 |
| Molecular Weight | 432.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
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Recommended Standards
- 2-(4-Chlorophenyl)-4-(2,3-dichloro-4-(ethylsulfonyl)phenyl)thiazole (CAS 672951-37-0)
- N-[(4-Chlorophenyl)methyl]-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241126-97-6)
- 2-(2-Chlorophenyl)-4-[2,3-dichloro-4-(ethanesulfonyl)phenyl]-1,3-thiazole (CAS 672951-36-9)
- Padsevonil (CAS 1294000-61-5)
- tert-Butyl ((1-((S)-2-aminopropanoyl)pyrrolidin-3-yl)methyl)carbamate (CAS 1354028-57-1)
- 4-Bromo-2-iodobenzyl bromide (CAS 885681-96-9)
- 2-(4-(4-Iodophenyl)-1H-pyrazol-1-yl)acetic acid (CAS 1399653-47-4)
- 4-(1H-Imidazol-1-yl)-2,2-dimethyl-7-phenylheptan-3-one (CAS 94743-44-9)
- DOTA-NHS-ester (CAS 170908-81-3)
- 2-(chloromethyl)-7-methyl-3H-imidazo[4,5-b]pyridine (CAS 1344054-57-4)
- 2-Amino-3-(4-(hydroxymethyl)phenyl)propanoic acid (CAS 15720-20-4)
- 8-(Bicyclo[2.2.1]heptan-2-yl)-2-chloro-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1956380-12-3)
- Ethyl 2-(4-bromo-2-fluoro-phenyl)acetate (CAS 924312-09-4)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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