2-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-oxoacetic acid CAS 1443312-00-2
| CAS No. | 1443312-00-2 |
| Molecular Formula | C9H4F4O4 |
| Molecular Weight | 252.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 252.12 g/mol gives 2-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-oxoacetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-oxoacetic acid (CAS 1443312-00-2) is a high-purity analytical reference standard with the molecular formula C9H4F4O4 and a molecular weight of 252.12 g/mol.
The molecular framework of 2-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-oxoacetic acid (C9H4F4O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4F4O4 |
| Molecular Weight | 252.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
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Recommended Standards
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- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (CAS 180091-38-7)
- 5-Chloro-7-fluoro-1H-indole-3-carbaldehyde (CAS 1227580-10-0)
- 4',4''',4''''',4'''''''-(ethene-1,1,2,2-tetrayl)tetrakis(([1,1'-biphenyl]-4-amine)) (CAS 2252187-21-4)
- Methyl (2Z)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanoate (CAS 339018-16-5)
- (4-(1-Hydroxycyclopropyl)phenyl)boronic acid (CAS 956006-93-2)
- 3-(Dimethoxymethyl)pyrrolidine (CAS 2229188-24-1)
- (6Z,9Z,12Z)-hexadeca-6,9,12,15-tetraenoic acid (CAS 86995-95-1)
- Methyl 2-(((tert-butoxycarbonyl)amino)methyl)thiazole-4-carboxylate (CAS 297165-32-3)
- 2-Amino-5-(trifluoromethyl)pyridine (CAS 74784-70-6)
- Ethyl 2-(4-(isopentyloxy)-2-methylphenyl)-2-oxoacetate (CAS 1443349-18-5)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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