Opicapone impurity 35 CAS 1443319-15-0
| CAS No. | 1443319-15-0 |
| Molecular Formula | C8H6ClNO5 |
| Molecular Weight | 231.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Opicapone impurity 35 (C8H6ClNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Opicapone impurity 35 (CAS 1443319-15-0) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6ClNO5 and a molecular weight of 231.59 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Opicapone impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO5 |
| Molecular Weight | 231.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Opicapone Standards
- Opicapone impurity 27 (CAS CATO-C4X-240427)
- Opicapone impurity 12 (CAS CATO-C4X-240412)
- Opicapone impurity 71 (CAS CATO-C4X-240471)
- Opicapone Impurity 02 (CAS 923288-59-9)
- Opicapone impurity 37 (CAS CATO-C4X-240437)
- Opicapone impurity 38 (CAS CATO-C4X-240438)
- Opicapone impurity 68 (CAS CATO-C4X-240468)
- Opicapone Impurity 8 (CAS CATO-C4X-24048)
Recommended Standards
- Methyl 5-chloro-2-hydroxy-3-nitrobenzoate (CAS 5043-79-8)
- 3-Chloro-7-(trifluoromethyl)quinoline (CAS 104612-21-7)
- Methyl 4-amino-6-chloro-5-nitronicotinate (CAS 2092721-53-2)
- 6-Chloro-8-(trifluoromethyl)quinoline (CAS 1065074-68-1)
- Ivermectin EP Impurity A (CAS 65195-55-3)
- Avacopan Impurity 6 (CAS 2763538-64-1)
- Darolutamide Impurity 38 (CAS CATO-C4X-310638)
- 1-Benzylpyrrolidine-3,4-dicarboxylic acid (CAS 885956-70-7)
- 4-(tert-Butyl)-3-hydroxybenzaldehyde (CAS 532966-59-9)
- 3-(3-Phenoxybenzamido)thiophene-2-carboxylic acid (CAS 849333-95-5)
- N-isopropyl-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241127-01-5)
- 3-Bromo-2,6-dimethoxybenzaldehyde (CAS 29866-51-1)
- Ethyl 2-(p-tolylthio)acetate (CAS 14738-27-3)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com