Avacopan Impurity 6 CAS 2763538-64-1
| CAS No. | 2763538-64-1 |
| Molecular Formula | C21H23FN2O3 |
| Molecular Weight | 370.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Avacopan Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Avacopan Impurity 6 (CAS 2763538-64-1), a pharmacopoeial impurity reference standard (molecular formula C21H23FN2O3, MW 370.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Avacopan Impurity 6 (C21H23FN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H23FN2O3 |
| Molecular Weight | 370.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Avacopan Standards
- Avacopan Impurity 2 (CAS 1346623-07-1)
- Avacopan Impurity 5 (CAS 1346623-09-3)
- Avacopan Impurity 4 (CAS 1346623-05-9)
- Avacopan Impurity 10 (CAS CATO-C4X-294510)
- Avacopan (CAS 1346623-17-3)
- Avacopan Impurity 12 (CAS CATO-C4X-294512)
- Avacopan impurity 7 (CAS 1257868-45-3)
- Avacopan Impurity 9 (CAS CATO-C4X-29459)
Recommended Standards
- Pimavanserin Impurity 41 (CAS CATO-C4X-193841)
- Esomeprazole-d3 Sodium Salt (CAS CATO-CCAD301902)
- Sulpiride impurity 14 (CAS CATO-C4X-187614)
- (3-((6-(2-Methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methanesulfonamide (CAS 1073485-20-7)
- Indometacin Impurity 23 (CAS CATO-C4X-147023)
- Ledipasvir Impurity 49 (CAS CATO-C4X-331349)
- Florfenicol Impurity 10 (CAS 3029320-86-0)
- 6-Iodo-5-(trifluoromethyl)nicotinamide (CAS 1496535-11-5)
- 1-(1,2,3,4-Tetrahydronaphthalen-1-yl)propan-2-ol (CAS 1340369-19-8)
- 3-((4-Aminopiperidin-1-yl)methyl)benzonitrile dihydrochloride (CAS 1286273-82-2)
- 6-Fluoro-1-(4-fluoro-2-methylphenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 164662-40-2)
- 5-((5-Chloro-4-((1-methylpiperidin-4-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CAS 1137477-49-6)
- (6-chloropyridazin-3-yl)methanamine (CAS 871826-15-2)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com