Enzalutamide Impurity 10 CAS 1443331-78-9
| CAS No. | 1443331-78-9 |
| Molecular Formula | C22H18F4N4O2S |
| Molecular Weight | 478.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Enzalutamide Impurity 10 (CAS 1443331-78-9) is a certified pharmaceutical impurity reference standard with the molecular formula C22H18F4N4O2S and a molecular weight of 478.46 g/mol.
Enzalutamide Impurity 10 (C22H18F4N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Enzalutamide Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H18F4N4O2S |
| Molecular Weight | 478.46 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity 49 (CAS CATO-C4X-101649)
- Enzalutamide Impurity 47 (CAS CATO-C4X-101647)
- Enzalutamide Impurity 4 (CAS 2030242-21-6)
- Enzalutamide Impurity 11 (CAS CATO-C4X-101611)
- Enzalutamide Impurity 28 (CAS CATO-C4X-101628)
- Enzalutamide-d6 (CAS 1443331-94-9)
- Enzalutamide Impurity 8 (CAS CATO-C4X-10168)
- Enzalutamide-d3 (CAS 1443331-82-5)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com