(2Z)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one CAS 956923-16-3
| CAS No. | 956923-16-3 |
| Molecular Formula | C27H21F3N2O3 |
| Molecular Weight | 478.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2Z)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one (CAS 956923-16-3) is a high-purity analytical reference standard with the molecular formula C27H21F3N2O3 and a molecular weight of 478.46 g/mol.
The molecular framework of (2Z)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one (C27H21F3N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2Z)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H21F3N2O3 |
| Molecular Weight | 478.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
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Recommended Standards
- N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (CAS 142038-31-1)
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- N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2-Deoxyguanosine (CAS 142038-30-0)
- Enzalutamide Impurity 10 (CAS 1443331-78-9)
- 2,5,7-Trimethyl-6-(3-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-23-6)
- 4-(Tert-butyl) 6-ethyl hexahydrofuro[3,2-b]pyridine-4,6(2H)-dicarboxylate (CAS 1887224-48-7)
- (Z)-N-(1-Bromo-1-(4-fluorophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl)benzamide (CAS 1800044-69-2)
- Ethyl 2-[(2-chlorophenyl)methyl]-1,3-thiazole-4-carboxylate (CAS 736970-78-8)
- 2-(6-Chloropyridazin-3-yl)isoindoline (CAS 1250115-88-8)
- 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine (CAS 50373-22-3)
- (E)-N-(((2,4-dichlorobenzyl)oxy)carbamoyl)-N'-methoxyformimidamide (CAS 338395-17-8)
- Chloronorbornadiene rhodium dimer (CAS 12257-42-0)
- Methyl 2-bromo-4,5-dihydroxy-3-methoxybenzoate (CAS 848772-95-2)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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