2-(3,5-Difluoro-2-isobutoxyphenyl)ethanol CAS 1443336-06-8
| CAS No. | 1443336-06-8 |
| Molecular Formula | C12H16F2O2 |
| Molecular Weight | 230.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3,5-Difluoro-2-isobutoxyphenyl)ethanol.
2-(3,5-Difluoro-2-isobutoxyphenyl)ethanol (CAS 1443336-06-8) is a high-purity analytical reference standard with the molecular formula C12H16F2O2 and a molecular weight of 230.25 g/mol.
2-(3,5-Difluoro-2-isobutoxyphenyl)ethanol (C12H16F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16F2O2 |
| Molecular Weight | 230.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Difluoro Standards
- (3,4-Difluoro-5-(pentyloxy)phenyl)methanol (CAS 1443306-00-0)
- 1-(3,4-Difluoro-5-isobutoxyphenyl)ethanol (CAS 1443310-04-0)
- (3,4-Difluoro-5-(isopentyloxy)phenyl)methanol (CAS 1443329-88-1)
- 2-(3,4-Difluoro-5-methoxyphenyl)-3-methylbutan-2-ol (CAS 1443333-48-9)
- 1-(3,5-Difluoro-4-isobutoxyphenyl)ethan-1-ol (CAS 1443335-10-1)
- (3,5-Difluoro-2-(isopentyloxy)phenyl)methanol (CAS 1443339-35-2)
- 3-(3,4-Difluoro-5-methoxyphenyl)pentan-3-ol (CAS 1443340-14-4)
- 2-(3,4-Difluoro-5-methoxyphenyl)pentan-2-ol (CAS 1443341-11-4)
Recommended Standards
- 2-(3-Butoxy-4,5-difluorophenyl)ethan-1-ol (CAS 1443335-41-8)
- 1-(2,2-Diethoxyethyl)-2,4-difluorobenzene (CAS 1443342-21-9)
- 2-(4-Butoxy-3,5-difluorophenyl)ethan-1-ol (CAS 1443310-24-4)
- 2-(3,5-Difluoro-4-isobutoxyphenyl)ethan-1-ol (CAS 1443343-45-0)
- 2-Chloro-3-(trifluoromethyl)quinoxaline (CAS 254732-51-9)
- 2-(Hydroxymethyl)-4-(trifluoromethyl)phenol (CAS 174265-02-2)
- 4-(2-Methyl-1,3-thiazol-4-yl)-1h-pyrrole-3-carboxylic acid (CAS 1096868-02-8)
- 1-Ethyl-1H-pyrrolo[3,2-b]pyridine (CAS 160590-41-0)
- 6-Amino-1H-indole-2-carbonitrile (CAS 873055-07-3)
- 3-(Cyclohex-2-en-1-yl)-4-hydroxy-1-methylquinolin-2(1H)-one (CAS 211686-40-7)
- 2-(2-Fluoro-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1150271-75-2)
- Amflutizole (CAS 82114-19-0)
- 2-(Azetidin-3-yloxy)-N-propylacetamide (CAS 1341137-62-9)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com