2-(Hydroxymethyl)-4-(trifluoromethyl)phenol CAS 174265-02-2

Purity 97%+In StockPharmaceutical Standards
CAS No.174265-02-2
Molecular FormulaC8H7F3O2
Molecular Weight192.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Hydroxymethyl)-4-(trifluoromethyl)phenol CAS 174265-02-2 chemical structure

Description

The occurrence of 2-(Hydroxymethyl)-4-(trifluoromethyl)phenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Hydroxymethyl)-4-(trifluoromethyl)phenol (CAS 174265-02-2) is a high-purity analytical reference standard with the molecular formula C8H7F3O2 and a molecular weight of 192.14 g/mol.

Structurally, 2-(Hydroxymethyl)-4-(trifluoromethyl)phenol (C8H7F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 192.14 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7F3O2
Molecular Weight192.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2006
Halogen ContentF-containing

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