Thiazol-2-yl(3-(trifluoromethyl)phenyl)methanone CAS 1443344-22-6
| CAS No. | 1443344-22-6 |
| Molecular Formula | C11H6F3NOS |
| Molecular Weight | 257.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.23 g/mol gives Thiazol-2-yl(3-(trifluoromethyl)phenyl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Thiazol-2-yl(3-(trifluoromethyl)phenyl)methanone (CAS 1443344-22-6) is a high-purity analytical reference standard with the molecular formula C11H6F3NOS and a molecular weight of 257.23 g/mol.
The molecular framework of Thiazol-2-yl(3-(trifluoromethyl)phenyl)methanone (C11H6F3NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Thiazol-2-yl(3-(trifluoromethyl)phenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6F3NOS |
| Molecular Weight | 257.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiazol Standards
- Thiazol-2-yl(4-(trifluoromethyl)phenyl)methanone (CAS 147878-71-5)
- N-(Thiazol-2-yl)quinoxaline-6-carboxamide (CAS 571910-89-9)
- 2-[2-(1,3-Thiazol-4-yl)ethyl]-1H-isoindole-1,3(2H)-dione (CAS 250258-56-1)
- N-(2-(Thiazol-4-yl)-1H-benzo[d]imidazol-6-yl)acetamide (CAS 27192-25-2)
- 2-[(5-methyl-1,3-thiazol-2-yl)thio]-1-thien-2-ylethanone (CAS 1000932-25-1)
- N-(Thiazol-2-yl)quinoline-2-carboxamide (CAS 313687-86-4)
- 1-(2-Oxo-2-(thiazol-2-ylamino)ethyl)pyrrolidine-3-carboxylic acid (CAS 1493016-28-6)
- Methyl 2-(thiazol-2-yl)-1H-benzo[d]imidazole-6-carboxylate (CAS 1535186-75-4)
Recommended Standards
- tert-Butyl (3,4-difluoro-2-formylphenyl)carbamate (CAS 144298-09-9)
- 5-(2-(Trifluoromethyl)phenyl)thiazole-2-carbaldehyde (CAS 1397236-07-5)
- 3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid (CAS 1485705-79-0)
- 5-(3-(Trifluoromethyl)phenyl)thiazole-2-carbaldehyde (CAS 1397180-25-4)
- (5,6-Dihydro-1,4-dioxin-2-yl)(morpholino)methanone (CAS 1240823-73-7)
- 4-Chloro-2-(cyclopentylsulfanyl)benzoic acid (CAS 1343726-37-3)
- METHYL 4-(1-AMINO-2-((TERT-BUTOXYCARBONYL)AMINO)ETHYL)BENZOATE (CAS 939760-52-8)
- 2-(4-Chloro-3-fluorobenzoyl)benzoic acid (CAS 2968-40-3)
- (3,4-Dimethylphenyl)(3-methylpyridin-2-yl)methanone (CAS 1187170-99-5)
- 4'-O-2,6-Dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl Selamectin (CAS 301849-46-7)
- 1-(tert-Butyl)imidazolidin-2-one (CAS 92075-16-6)
- 2-(Hydroxymethyl)pyrazolo[1,5-a]pyrimidin-5(4H)-one (CAS 1363210-36-9)
- 8-Ethoxy-3-phenyl-2H-oxazolo[2,3-b]quinazolin-5(3H)-one (CAS 52727-60-3)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
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