3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid CAS 1485705-79-0
| CAS No. | 1485705-79-0 |
| Molecular Formula | C12H13F2NO3 |
| Molecular Weight | 257.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.23 g/mol gives 3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid (CAS 1485705-79-0) is a high-purity analytical reference standard with the molecular formula C12H13F2NO3 and a molecular weight of 257.23 g/mol.
The molecular framework of 3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid (C12H13F2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2NO3 |
| Molecular Weight | 257.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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