Phenylbutyrate Impurity 5 CAS 1443417-17-1
| CAS No. | 1443417-17-1 |
| Molecular Formula | C13H18O4 |
| Molecular Weight | 238.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Phenylbutyrate Impurity 5 (C13H18O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Phenylbutyrate Impurity 5 (CAS 1443417-17-1), a pharmacopoeial impurity reference standard (molecular formula C13H18O4, MW 238.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18O4 |
| Molecular Weight | 238.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
Related Phenylbutyrate Standards
- Phenylbutyrate Impurity 16 (CAS CATO-C4X-258316)
- Phenylbutyrate Impurity 6 (CAS 1292210-87-7)
- Phenylbutyrate Impurity 9 (CAS 54698-75-8)
- Phenylbutyrate Impurity 14 (CAS 358349-85-6)
- Ethyl 4-Phenylbutyrate (CAS 10031-93-3)
- Sodium Phenylbutyrate (CAS 1716-12-7)
- Phenylbutyrate EP Impurity A (CAS 2051-95-8)
- Phenylbutyrate (Acid) (CAS 1821-12-1)
Recommended Standards
- Drotaverin Impurity 64 (CAS CATO-C4X-243564)
- Mirogabalin Impurity 116 (CAS CATO-C4X-2924116)
- Drotaverine Impurity 12 (CAS 92157-09-0)
- Mirogabalin Impurity 140 (CAS CATO-C4X-2924140)
- Roxadustat Impurity 57 (CAS 38791-58-1)
- Mosapride Impurity 69 (CAS CATO-C4X-104469)
- Varenicline Impurity 31 (CAS 1333145-89-3)
- Clopidogrel Impurity 15 (CAS 40412-06-4)
- 5-Bromo-N-cyclopropylpyridin-2-amine (CAS 885266-96-6)
- 2-Cyclohexanonecarboxylic acid ethyl ester (CAS 1655-07-8)
- (S)-2-amino-2-(2,3-difluorophenyl)ethan-1-ol (CAS 1213935-41-1)
- methyl 5-tert-butyl-1,3,4-oxadiazole-2-carboxylate (CAS 1565976-13-7)
- (1-Nonyl-1H-benzo[d]imidazol-2-yl)methanol (CAS 383371-87-7)
- Cyclopeptide-5 (CAS 197172-76-2)
Why CATO?
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