6-Fluoro-1h-benzimidazole-2-carboxylic acid hydrate CAS 1443425-13-5
| CAS No. | 1443425-13-5 |
| Molecular Formula | C8H5FN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Fluoro-1h-benzimidazole-2-carboxylic acid hydrate (CAS 1443425-13-5), molecular formula C8H5FN2O2H2O and molecular weight 198.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Fluoro-1h-benzimidazole-2-carboxylic acid hydrate (C8H5FN2O2H2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 6-Fluoro-1h-benzimidazole-2-carboxylic acid hydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5FN2O2 H2O |
| Molecular Weight | 198.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ajmaline (CAS 4360-12-7)
- (2-Benzoylphenyl)(4-(pyridazin-3-yloxy)piperidin-1-yl)methanone (CAS 1797755-04-4)
- 4-Isopropoxy-4’-nitrobenzophenone (CAS 221532-00-9)
- Diclazuril 6-Carboxylic Acid (CAS 862243-46-7)
- 3-Isobutyl-1H-pyrazole-4-carbaldehyde (CAS 199682-75-2)
- 2,5-Dibromo-3-ethoxypyridine (CAS 887571-07-5)
- 1-(2-Bromoethyl)-3-fluoro-5-(trifluoromethyl)benzene (CAS 955036-79-0)
- Ethyl 3-(trifluoromethyl)benzo[b]thiophene-2-carboxylate (CAS 1031929-14-2)
- 1-Bromo-3-methoxypropan-2-one (CAS 75522-04-2)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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