6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate CAS 1443425-14-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1443425-14-6
Molecular FormulaC8H5ClN2O2
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate CAS 1443425-14-6 chemical structure

Description

The occurrence of 6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate (CAS 1443425-14-6), molecular formula C8H5ClN2O2H2O and molecular weight 214.60 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 6-Chloro-1<I>H</I>-benzimidazole-2-carboxylic acid monohydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5ClN2O2 H2O
Molecular Weight214.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing
Nitrogen Atoms2

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