Bimatoprost Impurity 16 CAS 144358-71-4
| CAS No. | 144358-71-4 |
| Molecular Formula | C13H19O4P |
| Molecular Weight | 270.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bimatoprost Impurity 16 (C13H19O4P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Bimatoprost Impurity 16 (CAS 144358-71-4), a pharmacopoeial impurity reference standard (molecular formula C13H19O4P, MW 270.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H19O4P |
| Molecular Weight | 270.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related Bimatoprost Standards
- Bimatoprost Impurity M (CAS 41162-19-0)
- Bimatoprost Impurity 12 (CAS CATO-C4X-196412)
- Bimatoprost Impurity 2 (CAS 41639-74-1)
- Bimatoprost Impurity 21 (CAS 856240-62-5)
- Bimatoprost Impurity 25 (CAS 146964-27-4)
- Bimatoprost Impurity 11 (CAS CATO-C4X-196411)
- Bimatoprost Impurity 8 (CAS 76704-05-7)
- Bimatoprost Impurity 9 (CAS 32233-40-2)
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