Bimatoprost Impurity 21 CAS 856240-62-5
| CAS No. | 856240-62-5 |
| Molecular Formula | C18H24O4 |
| Molecular Weight | 304.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Bimatoprost Impurity 21 (C18H24O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Bimatoprost Impurity 21 (CAS 856240-62-5, C18H24O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bimatoprost Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24O4 |
| Molecular Weight | 304.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Bimatoprost Standards
- Bimatoprost Impurity 2 (CAS 41639-74-1)
- Bimatoprost Impurity 25 (CAS 146964-27-4)
- Bimatoprost Impurity 11 (CAS CATO-C4X-196411)
- Bimatoprost Impurity 16 (CAS 144358-71-4)
- Bimatoprost Impurity M (CAS 41162-19-0)
- Bimatoprost Impurity 12 (CAS CATO-C4X-196412)
- Bimatoprost Acid (CAS 38344-08-0)
- Bimatoprost Impurity 19 (CAS 41639-71-8)
Recommended Standards
- Loxoprofen Impurity 7 (CAS CATO-C4X-14887)
- Estetrol Impurity 5 (CAS CATO-C4X-32505)
- 1-hydroxypropan-2-yl 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate (CAS CATO-C4X-1488158)
- Estetrol Impurity 6 (CAS CATO-C4X-32506)
- Mitoxantrone Impurity 25 (CAS CATO-C4X-103425)
- Tocopherol Impurity 30 (CAS CATO-C4X-119530)
- Teneligliptin Impurity 53 (CAS 1572583-27-7)
- 5-Chloronaphthalene-1-carbothioamide (CAS 1354750-18-7)
- 3-(p-Tolyl)-1H-pyrazol-5(4H)-one (CAS 66076-78-6)
- 2-(3-Chlorophenyl)propan-1-amine (CAS 1082555-06-3)
- N-(2,3-dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332912-60-4)
- 1-(2,2-Dimethylmorpholino)-3-methylbut-2-en-1-one (CAS 1181876-21-0)
- 5-Bromo-3-trifluoromethylbenzo[b]thiophene-2-carboxylic acid methyl ester (CAS 617706-20-4)
- Compstatin control peptide (CAS 301544-78-5)
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