Istradefylline Impurity 13 CAS 14436-34-1
| CAS No. | 14436-34-1 |
| Molecular Formula | C4H5N3O2 |
| Molecular Weight | 127.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Istradefylline Impurity 13 (CAS 14436-34-1) is a certified pharmaceutical impurity reference standard with the molecular formula C4H5N3O2 and a molecular weight of 127.10 g/mol.
Structurally, Istradefylline Impurity 13 (C4H5N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 127.10 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C4H5N3O2 |
| Molecular Weight | 127.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 3 |
Related Istradefylline Standards
- Istradefylline impurity (CAS 49540-32-1)
- Istradefylline Impurity 14 (CAS 21237-00-3)
- Istradefylline Impurity 29 (CAS 5759-63-7)
- Istradefylline Impurity 21 (CAS 41740-15-2)
- Istradefylline Impurity 16 (CAS CATO-C4X-106116)
- Istradefylline Impurity 11 (CAS 52998-22-8)
- Istradefylline Impurity 8 (CAS 14773-40-1)
- Istradefylline impurity 38 (CAS CATO-C4X-106138)
Recommended Standards
- 2,4(1h,3h)-pyrimidinedione, 5-amino- 2,4-dihydroxy-5-aminopyrimidine 3h)-pyrimidinedione,5-amino-4(1h 5-Aminopyrimidine-2,4(1H,3H)-dione 5-amino-2,4(1h,3h)-pyrimidinedione 5-amino-2,4-dihydroxypyrimidine 5-amino-2,4-pyrimidinediol 5-amino-uraci 5-aminouracil 932-52-5 uracil, 5-amino- (CAS 932-52-5)
- Tofacitinib Impurity 117 (CAS 873-83-6)
- 2-Amino-6-hydroxypyrimidin-4(1H)-one (CAS 56-09-7)
- Dexmedetomidine Impurity 80 (CAS CATO-C4X-123080)
- Resmetirom impurity 111 (CAS CATO-C4X-2912111)
- Favipiravir Impurity 12 (CAS 62009-47-6)
- Ursodeoxycholic acid impurity 62 (CAS CATO-C4X-142262)
- N-Boc-3-bromoaniline (CAS 25216-74-4)
- 3-Isopropoxy-N-((1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)propan-1-amine hydrochloride (CAS 1856020-39-7)
- 1-Benzyl 6-Methyl (S)-2-(Boc-amino)-4-oxohexanedioate (CAS 630128-01-7)
- (1-Ethyl-1H-indol-7-yl)boronic acid (CAS 1357396-83-8)
- Ursodeoxycholic Acid Impurity 133 (CAS CATO-C4X-1422133)
- 2-[(3-fluorophenyl)methoxy]ethan-1-ol (CAS 851859-50-2)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com