2-Chloro-6-fluorophenyl trifluoromethanesulfonate CAS 1443684-70-5
| CAS No. | 1443684-70-5 |
| Molecular Formula | C7H3ClF4O3S |
| Molecular Weight | 278.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-fluorophenyl trifluoromethanesulfonate (CAS 1443684-70-5), molecular formula C7H3ClF4O3S and molecular weight 278.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-6-fluorophenyl trifluoromethanesulfonate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-fluorophenyl trifluoromethanesulfonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF4O3S |
| Molecular Weight | 278.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-fluorophenyl trifluoromethanesulphonate (CAS 1207669-20-2)
- 4-Chloro-2-fluorophenyl trifluoromethanesulphonate (CAS 154267-22-8)
- 6-Chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid (CAS 215122-07-9)
- 6-chloro-3-(2,2,2-trifluoro-1-hydroxyethyl)-4H-chromen-4-one (CAS 2922555-52-8)
- 7-chloro-3-(2,2,2-trifluoro-1-hydroxyethyl)-4H-chromen-4-one (CAS 2922555-49-3)
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- Ethyl 3-chloro-4-cyano-5-(trifluoromethyl)picolinate (CAS 1221792-27-3)
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Why CATO?
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