(R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide CAS 1443763-60-7
| CAS No. | 1443763-60-7 |
| Molecular Formula | C29H26FN5O4S |
| Molecular Weight | 559.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide.
CATO supplies (R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide (CAS 1443763-60-7), a certified reference material (molecular formula C29H26FN5O4S, MW 559.61 g/mol) for analytical method development and quality control.
The molecular framework of (R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide (C29H26FN5O4S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H26FN5O4S |
| Molecular Weight | 559.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related R Standards
- 4-Fluorophenyl)(triphenylphosphine)gold (CAS 24228-71-5)
- Tris(3-fluorophenyl)(octadecyl)silane (CAS 2794-05-0)
- 1-(4-Fluorophenyl)-3-({4-[(4-{[3-(4-fluorophenyl)-3-oxopropyl]sulfanyl}phenyl)sulfanyl]phenyl}sulfanyl)propan-1-one (CAS 882749-65-7)
- 1-(6-((6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)benzo[d]thiazol-2-yl)-3-(2-morpholinoethyl)urea (CAS 1116743-46-4)
- [2-(4-Fluorophenyl)ethynyl](triphenylphosphine)gold (CAS 113286-70-7)
- 1-[4-[Bis(4-Fluorophenyl)Methyl]Piperazin-1-Yl]-3-[2-[(2-Methoxyphenoxy)Methyl]-1,3-Thiazolidin-3-Yl]Propane-1,3-Dione (CAS 161364-79-0)
- 3-{1-[2-(2-fluorophenyl)-2-oxoethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}-1-(3-methoxyphenyl)urea (CAS 1796890-46-4)
- (6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-3-oxo-6-heptenoic Acid 1,1-Dimethylethyl Ester (CAS 947262-23-9)
Recommended Standards
- 4-Amino-1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 103285-21-8)
- 4''-(2-(2-(2-(2-(4-Nitrophenoxy)ethoxy)ethoxy)ethoxy)ethoxy)-[1,1':4',1''-terphenyl]-4-ol (CAS 1611477-45-2)
- CAS 2756307-47-6 (CAS 2756307-47-6)
- Olmesartan Impurity 8 (CAS CATO-C4X-10978)
- 34513-98-9 Ruthenium, tris(nitrato-kappaO)nitrosyl- Tris(nitrato-O)nitrosylruthenium EINECS 252-068-8 Ruthenium nitrite-nitrato complex Ruthenium nitrosyl nitrate Ruthenium nitrosyl trinitrate(III) (CAS 34513-98-9)
- trans-3-(Methylthio)cyclobutanamine Hydrochloride (CAS 2059915-02-3)
- 4-(Hydroxymethyl)-3-methylphenol (CAS 22574-58-9)
- 1236066-51-5 Hydroxy-[N-t-BOC-(2S)-Pyrrolidinyl]methyl Dimethyl Phosphonate tert-butyl (S)-2-((R)-(dimethoxyphosphoryl)(hydroxy)methyl)pyrrolidine-1-carboxylate (CAS 1236066-51-5)
- 1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-21-9)
- Fluticasone Impurity 37 (CAS 948565-92-2)
- Methyl 4-acetamido-5-bromo-2-hydroxybenzoate (CAS 89481-86-7)
- Ethyl 6-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate (CAS 2169217-84-7)
- trans-Crotononitrile(contains ca. 20% cis- isomer) (CAS 627-26-9)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com