Fluticasone Impurity 37 CAS 948565-92-2
| CAS No. | 948565-92-2 |
| Molecular Formula | C29H33F2NO7S |
| Molecular Weight | 577.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fluticasone Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Fluticasone Impurity 37 (CAS 948565-92-2, C29H33F2NO7S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C29H33F2NO7S, Fluticasone Impurity 37 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 577.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C29H33F2NO7S |
| Molecular Weight | 577.64 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity 94 (CAS CATO-C4X-165094)
- Fluticasone Impurity 28 (CAS CATO-C4X-165028)
- Fluticasone Furoate Impurity 5 (CAS CATO-C4X-32545)
- Fluticasone Impurity 55 (CAS CATO-C4X-165055)
- Fluticasone Impurity N7 (CAS 80474-27-7)
- Fluticasone Impurity 103 (CAS CATO-C4X-1650103)
- Fluticasone Furoate EP Impurity G (CAS 785806-96-4)
- Fluticasone Impurity 25 (CAS 1374153-88-4)
Recommended Standards
- 1315329-43-1 (E)-N-(4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl)-4-methylbenzamide MFCD28167804 HG6-64-1 (CAS 1315329-43-1)
- Argatroban Impurity 44 (CAS 74874-09-2)
- CAS 1062642-68-5 (CAS 1062642-68-5)
- Argatroban Impurity 53 (CAS CATO-C4X-100753)
- Dotinurad Impurity 37 (CAS CATO-C4X-249437)
- Agomelatine Impurity 19 (CAS 99416-97-4)
- Goserelin Impurity 20 (CAS CATO-C4X-192020)
- 2,2-Difluoro-6-iodo-4-methylbenzo[d][1,3]dioxole-5-carboxylic acid (CAS 2451903-36-7)
- (3-Chloro-5-methylpyridin-4-yl)methanamine (CAS 1393584-10-5)
- 2-(2-(2-Amino-4-methylpyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol (CAS 1033739-92-2)
- 4-Benzhydrylpiperazin-1-amine dihydrochloride (CAS 1172327-56-8)
- 1-(Adamantan-1-yl)-2,2-dibromoethanone (CAS 26525-25-7)
- 2-(2,2,3-Triphenylcyclopropyl)phenol (CAS 64024-55-1)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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