Linezolid Impurity 14 CAS 1445-69-8
| CAS No. | 1445-69-8 |
| Molecular Formula | C8H6N2O2 |
| Molecular Weight | 162.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Linezolid Impurity 14 (C8H6N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 162.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Linezolid Impurity 14 (CAS 1445-69-8, C8H6N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6N2O2 |
| Molecular Weight | 162.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Linezolid Standards
- Linezolid Impurity 65 (CAS CATO-C4X-107365)
- Linezolid Impurity 13 (CAS 369-34-6)
- Linezolid Impurity 39 (CAS 39608-52-1)
- Linezolid Impurity 77 (CAS 3920-11-4)
- Linezolid Impurity 40 (CAS 224323-47-1)
- Linezolid Impurity 97 (CAS 384344-17-6)
- Linezolid Impurity 81 (CAS 38711-20-5)
- Linezolid Impurity 96 (CAS 152139-76-9)
Recommended Standards
- Axitinib Impurity 37 (CAS CATO-C4X-107137)
- Temozolomide Impurity 17 (CAS CATO-C4X-135317)
- Topiroxostat impurity 71 (CAS CATO-C4X-105571)
- Polaprezinc impurity 32 (CAS CATO-C4X-182132)
- Ertugliflozin impurity 10 (CAS 1689522-89-1)
- Perindopril Impurity 99 (CAS 145513-63-9)
- Linagliptin Impurity 17 (CAS 6140-11-0)
- tert-Butyl (S)-2-(3,4-dimethoxybenzyl)piperazine-1-carboxylate (CAS 1260587-68-5)
- (S)-2-amino-3-(3-(aminomethyl)phenyl)propanoic acid (CAS 57213-47-5)
- 1-(2-Cyclopropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1710195-35-9)
- (5-Bromo-2-fluorophenyl)methanol (CAS 99725-13-0)
- 2-Chloro-4-(1-chlorovinyl)pyridine (CAS 1314977-76-8)
- 3-(Pyridin-3-yloxy)propane-1-sulfonyl chloride (CAS 1340044-51-0)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
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