1-Bromo-2-fluoro-3-(methylsulfonyl)-5-nitrobenzene CAS 1445995-73-2
| CAS No. | 1445995-73-2 |
| Molecular Formula | C7H5BrFNO4S |
| Molecular Weight | 298.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-2-fluoro-3-(methylsulfonyl)-5-nitrobenzene.
1-Bromo-2-fluoro-3-(methylsulfonyl)-5-nitrobenzene (CAS 1445995-73-2) is a high-purity analytical reference standard with the molecular formula C7H5BrFNO4S and a molecular weight of 298.09 g/mol.
1-Bromo-2-fluoro-3-(methylsulfonyl)-5-nitrobenzene (C7H5BrFNO4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5BrFNO4S |
| Molecular Weight | 298.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- Ethyl 2-bromo-8-oxo-5,8-dihydropyrido[3,2-d]pyrimidine-7-carboxylate (CAS 1098588-16-9)
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- Ethyl 7-bromo-4-oxo-4H-pyrimido[1,2-a]pyrimidine-3-carboxylate (CAS 1352394-04-7)
- 1-Bromo-5-fluoro-4-methanesulfonyl-2-nitrobenzene (CAS 1415819-92-9)
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- (3-Bromo-5-phenoxy-1H-1,2,4-triazol-1-yl)acetic acid (CAS 1807979-68-5)
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Recommended Standards
- Methyl 2,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1529775-71-0)
- 1-((5-Bromofuran-2-yl)methyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1410167-24-6)
- Ethyl 3-(6-bromopyridin-3-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 1393575-99-9)
- Methyl 2,3-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1621256-23-2)
- 69974-54-5 Capryl alcohol-d18 DTXSID00480823 (CAS 69974-54-5)
- N-Hydroxy-3-(2-methyl-1H-benzo[d]imidazol-1-yl)propanimidamide (CAS 537696-12-1)
- N-(4-chlorophenyl)-2-methyl-2-(3-(trifluoromethyl)quinoxalin-2-yl)hydrazine-1-carboxamide (CAS 338773-11-8)
- Methyl 2-bromo-8-methoxyindolizine-7-carboxylate (CAS 1706460-06-1)
- 3-(Pyridin-3-yl)-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine] (CAS 1422137-80-1)
- 2-(2-Methyl-4-phenyloxazol-5-yl)acetic acid (CAS 89150-41-4)
- N-methyl-1-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)methanamine (CAS 857283-77-3)
- (2S,3S)-2-((S)-1-(2-Aminoacetyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid (CAS 89187-15-5)
- CCT018159, >98% (HPLC) (CAS 171009-07-7)
- Exenatide (CAS 141758-74-9（free base）)
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