tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate CAS 1446443-06-6
| CAS No. | 1446443-06-6 |
| Molecular Formula | C18H25BN2O4 |
| Molecular Weight | 344.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate (CAS 1446443-06-6), molecular formula C18H25BN2O4 and molecular weight 344.21 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate (C18H25BN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 344.21 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H25BN2O4 |
| Molecular Weight | 344.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Carbamic acid N-[4-cyano-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,1-dimethylethyl ester (CAS 1384313-04-5)
- 3-Methoxy-1-(4-methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1662682-34-9)
- tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate (CAS 1383851-37-3)
- 6-(3-Bromophenyl)-3-(pyrrolidin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706432-80-5)
- Spiro[2.3]Hexan-4-ylmethanol (CAS 19740-26-2)
- 2-((4-Ethyl-5-(4-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 462066-81-5)
- 6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 338412-46-7)
- (-)-Isobicyclogermacrenal (CAS 73256-82-3)
- Methyl 5-Amino-2-chloro-4-methylbenzoate (CAS 1143026-47-4)
- 3-(dimethylamino)cyclobutan-1-ol (CAS 18126-77-7)
- N-(3-phenylprop-2-yn-1-yl)butan-1-amine hydrochloride (CAS 1048947-48-3)
- 1-(2-Bromophenyl)-2-(4-ethylpiperazin-1-yl)ethan-1-one (CAS 736166-36-2)
- 5-Isopropyl-5-methyl-2-(methylamino)-1H-imidazol-4(5H)-one (CAS 126973-50-0)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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