methyl 2-amino-4-fluoro-2-methylbutanoate CAS 1446499-77-9
| CAS No. | 1446499-77-9 |
| Molecular Formula | C6H12FNO2 |
| Molecular Weight | 149.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including methyl 2-amino-4-fluoro-2-methylbutanoate.
CATO supplies methyl 2-amino-4-fluoro-2-methylbutanoate (CAS 1446499-77-9), a certified reference material (molecular formula C6H12FNO2, MW 149.16 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H12FNO2, methyl 2-amino-4-fluoro-2-methylbutanoate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 149.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H12FNO2 |
| Molecular Weight | 149.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- (R)-2-Amino-4-fluoro-4-methylpentanoic acid (CAS 1447694-62-3)
- (S)-2-Amino-4-fluoro-4-methylpentanoic Acid (CAS 857026-04-1)
- 2-Amino-3-fluorohexanoic acid (CAS 43163-96-8)
- 2-Amino-6-fluorohexanoic acid (CAS 368-30-9)
- 6-Amino-1H-benzo[d]imidazol-4-ol (CAS 100868-28-8)
- 1-Amino-1H-benzo[d]imidazol-2(3H)-one (CAS 102616-91-1)
- 4-Amino-5-methoxynicotinonitrile (CAS 1142192-15-1)
- 7-Amino-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (CAS 115012-14-1)
Recommended Standards
- 1-(2-Fluorophenyl)prop-2-yn-1-amine (CAS 1420793-91-4)
- 5-Fluoro-3,4-dihydroisoquinoline (CAS 1355060-41-1)
- 2-Fluoro-1-methyl-1H-indole (CAS 144951-50-8)
- 7-Fluoro-6-methyl-1H-indole (CAS 1352395-29-9)
- 1-(4-Hydroxy-2,6-bis(trifluoromethyl)phenyl)ethanone (CAS 1805208-04-1)
- 1017778-27-6 5-Methyl-2-(trifluoromethyl)phenylacetic acid MFCD09832298 (CAS 1017778-27-6)
- Fmoc-β-(2,2-dimethyl-4H-benzo[1,3]dioxin-6-yl)-Ala-OH (CAS 252049-13-1)
- 4-Ethoxy-N-methoxy-N-methylbenzamide (CAS 1221341-06-5)
- Nintedanib Impurity 69 (CAS 2380229-45-6)
- Heptane-2,4-dione (CAS 7307-02-0)
- 5,7-Dimethylpyrazolo[1,5-a]pyrimidin-2-amine (CAS 1605-78-3)
- 4,4,6-Trimethyl-2-(naphthalen-2-yl)-1,3,2-dioxaborinane (CAS 1260068-92-5)
- Methyl 4-bromo-3-cyano-5-fluorobenzoate (CAS 1805246-26-7)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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