1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine CAS 1446712-64-6
| CAS No. | 1446712-64-6 |
| Molecular Formula | C12H8FIN4 |
| Molecular Weight | 354.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 354.12 g/mol gives 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine (CAS 1446712-64-6), a certified reference material (molecular formula C12H8FIN4, MW 354.12 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine (C12H8FIN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8FIN4 |
| Molecular Weight | 354.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 4 |
Related Fluorobenzyl Standards
- 1-(2-Fluorobenzyl)-3-(2,4,6-trimethylbenzyl)imidazolidine-2,4,5-trione (CAS 303986-41-6)
- 6-Ethyl-2-((3-fluorobenzyl)thio)-5-methyl-4-(trifluoromethyl)nicotinonitrile (CAS 664994-27-8)
- 2-((4-Fluorobenzyl)thio)-9-methyl-5H-thiochromeno[4,3-d]pyrimidine (CAS 478246-80-9)
- 2-(2-((2-Fluorobenzyl)thio)-5-(hydroxymethyl)-1H-imidazol-1-yl)-N-(2-methoxyethyl)acetamide (CAS 921820-53-3)
- (E)-4-(2-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)vinyl)benzonitrile (CAS 400079-47-2)
- 3-(4-Fluorobenzyl)-4-hydroxy-1-(1-hydroxy-3-phenylpropan-2-yl)pyridin-2(1H)-one (CAS 477856-04-5)
- 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine (CAS 1313738-72-5)
- 4-((3-Fluorobenzyl)oxy)-3-iodobenzonitrile (CAS 1706445-12-6)
Recommended Standards
- 4,4′-dibromobiphenyl-2,2′-diamine (CAS 136630-36-9)
- 6-Fluoro-2-(3-iodophenyl)-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706437-37-7)
- Ethyl 2-(2,4-dichlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylate (CAS 1431728-96-9)
- Diethyl (4-iodobenzyl)phosphonate (CAS 173443-43-1)
- 4,4-Difluoropyrrolidine-2-carbonitrile hydrochloride (CAS 2225136-14-9)
- N-(4-acetylphenyl)-2-bromopropanamide (CAS 1171221-51-4)
- n-Benzyl-4-nitrobenzamide (CAS 2585-26-4)
- 898788-40-4 (4-Methoxyphenyl){3-[(4-methylpiperazin-1-yl)methyl]phenyl}methanone DTXSID60643412 (CAS 898788-40-4)
- <SC>DL</SC>-Sodium 3-hydroxybutyrate-1-<SUP>13</SUP>C (CAS 1173022-79-1)
- 3,7,7-TRIMETHYLBICYCLO[4.1.0]HEPTAN-2-ONE (CAS 497-62-1)
- 3,4-Dihydro-2H-pyran-6-methanol (CAS 72081-17-5)
- 26062-48-6 Polyhistidine L-Histidine, homopolymer Poly(L-histidine) (CAS 26062-48-6)
- 2-(2-Acetamidothiazol-4-yl)-N-(2,6-difluorobenzyl)acetamide (CAS 923675-71-2)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com